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100 Houstonians in Harris and Ft. Bend Counties Awarded a Total of $1 Million Through Comcast RISE, National Initiative to Support Small Business Owners

Comcast Houston

Comcast today announced the 100 recipients of the Comcast Rise Investment Fund grants. Each small business will receive a one-time $10,000 grant from the fund. More than 100 businesses in the area will also receive technology and marketing resources. The recipients are among nearly 6,700 entrepreneurs nationwide who have been selected through the Comcast RISE program, which provides marketing, technology, and capital support to small business owners. “We are proud of all of our small businesses, the impact they have in Fort Bend County is invaluable. Many of our business owners, particularly our minority owned businesses, have faced unprecedented challenges over the past year due to the COVID-19 pandemic, and require a wide range of support to help their businesses survive,” stated Fort Bend County Judge KP George. “The Comcast Rise Investment Fund Grant provides these business owners with the critical financial lifeline and the resources needed so they can sustain and grow their businesses.” Through Comcast RISE, the company also announced it is on track to support 13,000 small businesses by the end of the year with marketing or technology support such as a TV campaign, production of a TV commercial or consulting services from Effectv, the advertising sales division of Comcast Cable, or computer equipment, internet, voice or cybersecurity services from Comcast Business. “Since we launched Comcast RISE a year ago, we have assisted more than 200 small businesses throughout the Houston area with either marketing, technology, or monetary grants. This round of Comcast RISE grants will provide even more small business owners of color with the resources and tools they need to thrive,” said Ralph Martinez, senior vice president for Comcast’s Houston region. “We look forward to empowering their success.” To further build on the program’s success and provide support to even more small businesses, Comcast also announced today a major expansion to eligibility, enabling all women-owned small businesses nationwide to apply. This expansion recognizes and seeks to help address the persistent inequities women continue to face in accessing the resources and funding that are critical to success. Comcast RISE and the Comcast RISE Investment Fund, initially launched as a response to help small businesses owners of color hardest hit by the economic impacts of the COVID-19 pandemic, continue to focus on uplifting small businesses, ensuring they continue to prosper in an ever-shifting post-pandemic economy. “As we continue to rebuild and emerge from the effects of the pandemic, small businesses will continue to be the backbone of our economy – and we must take every opportunity to help them thrive,” said Dave Watson, President and CEO, Comcast Cable. “Looking forward, this expansion will enable Comcast RISE to further empower and strengthen even more small businesses that are the heart of our local communities across the country.” In the year since its inception, Comcast RISE has awarded more than $11 million in grants and $50 million in in-kind support for marketing and technology services, impacting more than 6,700 entrepreneurs of color in 432 cities across 34 states. By the end of 2022, 13,000 businesses across the country are expected to benefit from the Comcast RISE initiative, either through the grant program or from the resources provided through Effectv and Comcast Business. In addition to the financial and business support services provided, a key part of the program is ensuring the long-term sustainability of businesses. To help address this, Comcast invests in and partners with organizations such as Ureeka to provide ongoing mentorship and resources to help small businesses succeed over the long-term. Comcast RISE, which stands for Representation, Investment, Strength, and Empowerment, is part of Project UP, Comcast’s comprehensive initiative to advance digital equity and help provide underrepresented small business owners with access to the digital tools and funding they need to thrive. Over the next 10 years, Comcast has committed $1 billion to programs and partnerships that will reach an estimated 50 million people with the skills, opportunities, and resources they need to succeed in an increasingly digital world. The program will continue to be open to racially and ethnically diverse small business owners and the expanded Comcast RISE eligibility to all women-owned businesses will be effective on January 16, 2022. More information and the applications to apply for either the grant program or marketing and technology services are available at www.ComcastRISE.com. To help drive outreach and awareness about Comcast RISE and provide additional support, training and mentorship, Comcast has also awarded $50,000 in grants to local community partners – Houston Hispanic Chamber, Houston Black Chamber, Empresarios Latinos Foundation, Houston LGBT Chamber, Asian Chamber of Commerce, Greater Houston Women’s Foundation and East End Chamber of Commerce. About Comcast Corporation Comcast Corporation (Nasdaq: CMCSA) is a global media and technology company that connects people to moments that matter. We are principally focused on broadband, aggregation, and streaming with 57 million customer relationships across the United States and Europe. We deliver broadband, wireless, and video through our Xfinity, Comcast Business, and Sky brands; create, distribute, and stream leading entertainment, sports, and news through Universal Filmed Entertainment Group, Universal Studio Group, Sky Studios, the NBC and Telemundo broadcast networks, multiple cable networks, Peacock, NBCUniversal News Group, NBC Sports, Sky News, and Sky Sports; and provide memorable experiences at Universal Parks and Resorts in the United States and Asia. Visit www.comcastcorporation.com for more information. About Comcast Business Comcast Business offers a suite of Connectivity, Communications, Networking, Cybersecurity, Wireless, and Managed Solutions to help organizations of different sizes prepare for what’s next. Powered by the nation’s largest Gig-speed broadband network, and backed by 24/7 customer support, Comcast Business is the nation’s largest cable provider to small and mid-size businesses and one of the leading service providers to the Enterprise market. Comcast Business has been consistently recognized by industry analysts and associations as a leader and innovator, and one of the fastest growing providers of Ethernet services. For more information, call 866-429-3085. Follow on Twitter @ComcastBusiness and on other social media networks at http://business.comcast.com/social. About Effectv Effectv, the advertising sales division of Comcast Cable, helps local, regional and national advertisers use the best of digital with the power of TV to grow their business. It provides multi-screen marketing solutions to make advertising campaigns more effective and easier to execute. Headquartered in New York with offices throughout the country, Effectv has a presence in 66 markets with nearly 35 million owned and represented subscribers. For more information, visit www.effectv.com. Contact Details Comcast Foti Kallergis +1 832-986-0196 Foti_Kallergis@comcast.com Comcast Misha McClure +1 832-547-6783 Misha_McClure@cable.comcast.com Company Website https://houston.comcast.com/

November 23, 2021 09:31 AM Central Standard Time

ONCOTELIC ANNOUNCES POSITIVE TOPLINE DATA FOR OT-101 C001 COVID STUDY

Oncotelic Therapeutics

Oncotelic Therapeutics, Inc. ("Oncotelic" or the "Company") (OTCQB:OTLC), a leading developer of TGF-β therapeutics for oncology and virology, today announced that its COVID-19 trial (“C001”) for OT-101 has successfully met its safety and efficacy endpoints. OT-101 is a first-in-class anti-TGF-β ribonucleic acid (“RNA”) therapeutic that has exhibited single agent activity in relapsed/refractory cancer patients in multiple clinical trials. OT-101 has also demonstrated activity against the SARS-CoV-2 virus, the virus that causes COVID-19, and is currently being evaluated in the Company’s C001 clinical trial against hospitalized severe COVID-19 patients. Both tumor cells and SARS-Cov-2 induce TGF-β as part of their immune evasion mechanism. Consequently, inhibiting TGF-β by OT-101 is expected to impact both cancer and COVID. By targeting the host protein, OT-101 is expected to work against multiple respiratory viruses, including related emerging variants, unlike traditional antiviral drugs and vaccines. On October 18, Data lock and Study Data and Analysis Data Models (SDTMs & ADaMS Databases) were generated for a Phase 2 C001 Covid Study: “A Double-Blind, Randomized, Placebo Controlled, Multi-Center Study of OT-101 in Hospitalized COVID-19 Subjects”. The trial compares OT-101 + Standard of Care (“SOC”) versus Placebo + SOC (N= 32 patients, at 2:1 randomization ratio). SOC includes dexamethasone, the only drug known to improve outcomes in severe cases of COVID-19. The top line data is: Safety endpoints met. OT-101 as a TGF-β inhibitor was safe to administer to COVID-19 patients including severe/critical COVID-19 patients. Efficacy signals were obtained. End of treatment (Day 7) mortality for the entire study population was 4.5% OT-101 versus 20% for placebo. Incidence of >96% viral load knockdown on End of Treatment (Day 7) was 89% for OT-101 versus 67% for placebo. Overall survival improved 3X for critical COVID-19 patients (4 days for placebo versus 14 days for OT-101, p < 0.0166). “It is gratifying that the TGF-β concept that we put forward has now been validated,” said Dr. Vuong Trieu, CEO and Chairman of Oncotelic. “The data form the basis for further development of OT-101 as a viable treatment for severe respiratory viral infections, including flu and COVID-19. We thank the patients and investigators involved, especially Dr. Carbajal of Calle Mariscal Sucre, Chancay, Huaral, Lima, Peru, who drove the study to its conclusion.” “The resulting data clearly suggest a favorable clinical response to OT-101 in the treatment of patients with COVID-19,” noted Dr. Anthony Maida, Chief Clinical Officer – Translational Medicine. “Additionally, we were able to demonstrate that there is no evidence of delivering OT-101 and any effect relating to cytokine release syndrome.” Oncotelic Therapeutics, Inc. ("Oncotelic" or the "Company") (OTCQB:OTLC), a leading developer of TGF-beta therapeutics for oncology and virology. This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements, other than statements of historical facts, included in this communication regarding strategy, future operations, future financial position, prospects, plans and objectives of management are forward-looking statements. Words such as "may", "expect", "anticipate" "hope", "vision", "optimism", "design", "exciting", "promising", "will", "conviction", "estimate," "intend," "believe", "quest for a cure of cancer", "innovation-driven", "paradigm-shift", "high scientific merit", "impact potential" and similar expressions are intended to identify forward-looking statements. Forward looking statements contained in this press release include, but are not limited to, statements about future plans, the progress, timing, clinical development, scope and success of future clinical trials, the reporting of clinical data for the company's product candidates and the potential use of the company's product candidates to treat various cancer indications. Each of these forward-looking statements involves risks and uncertainties, and actual results may differ materially from these forward-looking statements. Many factors may cause differences between current expectations and actual results, including unexpected safety or efficacy data observed during preclinical or clinical studies, clinical trial site activation or enrollment rates that are lower than expected, changes in expected or existing competition, changes in the regulatory environment, failure of collaborators to support or advance collaborations or product candidates and unexpected litigation or other disputes. These risks are not exhaustive, the company faces known and unknown risks, including the risk factors described in the Company's annual report on Form 10-K filed with the SEC on April 15, 2021 and in the company's other periodic filings. Forward-looking statements are based on expectations and assumptions as of the date of this press release. Except as required by law, the company does not assume any obligation to update forward-looking statements contained herein to reflect any change in expectations, whether as a result of new information future events, or otherwise. About Oncotelic Therapeutics Oncotelic Therapeutics, Inc. (f/k/a Mateon Therapeutics, Inc.) ("Oncotelic"), was formed in the State of New York in 1988 as OXiGENE, Inc., was reincorporated in the State of Delaware in 1992, and changed its name to Mateon Therapeutics, Inc. in 2016, and Oncotelic Therapeutics, Inc. in November 2020. Oncotelic is an artificial intelligence driven immuno-oncology company with a robust pipeline of first in class TGF-beta immunotherapies for late stage cancers such as gliomas, pancreatic cancer and melanoma. OT-101, the lead immuno-oncology drug candidate of Oncotelic, is a first-in-class anti-TGF-beta RNA therapeutic that exhibited single agent activity in relapsed/refractory cancer patients. OT-101 also has shown activity against SARS-CoV-2 and has completed a phase 2 trial against COVID-19 with data cleaning and datalock ongoing. Oncotelic is seeking to leverage its deep expertise in oncology drug development to improve treatment outcomes and survival of cancer patients with a special emphasis on rare pediatric cancers. Oncotelic also has rare pediatric designation for DIPG (OT-101), melanoma (CA4P), and AML (OXi 4503). The Company also acquired PointR Data Inc. ("PointR") in November 2019. For more information, please visit www.oncotelic.com. Contact Details Oncotelic Therapeutics Inc Amit Shah ashah@onoctelic.com Company Website https://www.oncotelic.com

November 23, 2021 07:00 AM Eastern Standard Time

U.S. Government Settles Wrongful Death Lawsuit for $1 Million After Suicide Outside Georgia VA Medical Center

Bertling Law Group

The estate of a Navy veteran, who died by suicide after he was denied medical treatment at a Department of Veteran’s Affairs medical center, recently negotiated a $1 million settlement with the U.S. government as compensation for the 35 days of pain and suffering the veteran experienced before his death. The lawsuit, filed by the Bertling Law Group on behalf of the estate of Gary Steven Pressley, continues against Bobby Dodd Institute, an independent contractor responsible for operating the switchboard at the Carl Vinson VA Medical Center. The lawsuit alleges that Pressley’s family notified an employee of Bobby Dodd Institute that Pressley was in the parking lot with a loaded gun and intended to shoot himself. The lawsuit states that employee Elaine Carswell did not call the onsite VA police who could have reached Pressley in minutes with officers trained to deescalate such situations. Pressley died from a self-inflicted gunshot wound in the parking lot of the VA Medical Center. According to the lawsuit, Pressley’s referral to a pain specialist was never scheduled and he experienced excruciating pain after being denied pain medication previously prescribed by a community pain specialist. Pressley took his own life after his VA primary care physician negligently reduced his pain medication and failed to ensure he saw a new community pain management specialist in a timely fashion. Pressley’s referral to the pain specialist was never scheduled because the VA employee responsible for processing the appointment was overworked, overwhelmed and her department was understaffed. Pressley was honorably discharged from the United States Navy with an exemplary record following a tragic car accident that left him with serious injuries to his legs, hip, pelvis, and back. He required assistance to walk and managed considerable pain daily. He had previously been seen by a community pain specialist who was referred through the VA and his life had improved considerably. The community pain specialist stopped treating veterans because the VA was not paying for her services. Pressley was furthering his education and making plans to lead a long and healthy life when the VA failed to assign him a new pain specialist. His condition deteriorated because he did not receive needed prescription pain medicine for several weeks. He reached a breaking point on April 5, 2019 and shot himself in the chest. According to attorney Peter Bertling, Pressley’s death was imminently preventable. “Gary Steven Pressley served his country admirably and had been on a path to lead a long and happy life before the negligence of the Bobby Dodd Institute brought his life to a tragic close,” said Bertling. “Had Ms. Carswell paid attention to the family’s direct warnings, Pressley would still be here today.” Bertling Law Group can help you access all available resources for compensation. Prior to providing veteran advocacy, our attorneys spent three decades defending hospitals, nurses, and doctors accused of wrongdoing, helping to spare insurance companies millions of dollars in unsubstantiated damages. We now use that insight to help injured patients recover the damages to which they are entitled. More information is available at 844-295-7558 or BertlingLawGroup.com Download a copy of the complaint here and at www.LawsuitPressRelease.com. Contact Details LawsuitPressRelease.com John P. David +1 888-859-6637 john@lawsuitpressrelease.com Company Website https://www.bertlinglawgroup.com/

November 22, 2021 01:44 PM Eastern Standard Time

American Kidney Fund Commends the U.S. House of Representatives for Including Provisions for Kidney Patients in the Build Back Better Act

American Kidney Fund

The American Kidney Fund (AKF) applauds the U.S. House of Representatives for including provisions in the Build Back Better Act that will help people with chronic kidney disease (CKD) and kidney failure (end-stage renal disease, or ESRD). “Access to affordable, comprehensive health insurance and primary care physicians is the first step to ensuring that CKD is found early, which can provide kidney patients with early interventions that can slow or halt the progression of the disease,” said LaVarne A. Burton, President and CEO of the American Kidney Fund. “Enhancing Affordable Care Act (ACA) tax credits and strengthening the Medicaid program so more people in the United States can access affordable health insurance has been a longstanding policy priority of AKF. We are so pleased to see these provisions in the Build Back Better Act, as they will help kidney patients who rely on Medicaid, Medicare and private insurance.” Medicaid, which currently provides health coverage for one in five low-income individuals, plays a vital role in helping people prevent and manage chronic health conditions. Expanding Medicaid is an important step in helping people with CKD and ESRD. Compared to states that did not expand Medicaid, people living in states that expanded the program had lower mortality rates after going on dialysis and more patients were preemptively placed on the transplant list so they could be on dialysis for a shorter time. Medicaid expansion also resulted in improved measures of blood pressure and glucose, which is meaningful because diabetes and hypertension account for 75% of new cases of kidney failure. The Build Back Better Act includes a provision that would provide access to ACA coverage to individuals who live in states where there is a coverage gap because the state did not expand Medicaid. These individuals have incomes too high for Medicaid, but too low to qualify for ACA tax subsidies. The Build Back Better Act would expand ACA tax credits until 2025 to the lower income threshold, so they could gain access to health insurance. Additionally, AKF advocated for increased Federal Medical Assistance Percentage (FMAP), which is the federal portion of the federal-state funded program of Medicaid. The Build Back Better Act would expand FMAP from 90% to 93% from 2023 to 2025. As many states are facing budget shortfalls due to the COVID-19 pandemic, states could roll back Medicaid services. The additional funding is necessary to better ensure people retain access to the health care services they need. Access to medically-appropriate prescription drugs for kidney patients must be preserved amid federal efforts to address the rising cost of prescription drugs. Patients with CKD, ESRD and who are living with kidney transplants rely on prescription drugs to manage their kidney disease and comorbidities. Most people in the U.S. who are on dialysis are on Medicare, and AKF supports policies that would result in lower drug costs and lower out-of-pocket costs for them, including a restructuring of the Medicare Part D benefit that creates a true out-of-pocket cap for beneficiaries with a smoothing mechanism. The Build Back Better Act includes a $2,000 cap. Patients who reach that $2,000 prescription drug cap in the first month will have a mechanism to pay that $2,000 over the course of months to ensure affordability. The ACA expanded access to health insurance for millions of Americans, which has helped CKD patients receive early interventions to slow the progression of their disease. AKF supports expanding advanced premium tax credits (APTCs) so insurance is more affordable. The American Rescue Plan expanded APTCs to those who make more than 400% of poverty and capped insurance premium costs to 8.5% of the income. The Build Back Better Act would extend these provisions until 2025. The provision will allow millions of Americans to retain their health insurance, which is vital for those with diabetes, heart disease, CKD and ESRD. ### About the American Kidney Fund The American Kidney Fund (AKF) fights kidney disease on all fronts as the nation’s leading kidney nonprofit. AKF works on behalf of the 37 million Americans living with kidney disease, and the millions more at risk, with an unmatched scope of programs that support people wherever they are in their fight against kidney disease—from prevention through transplant. With programs that address early detection, disease management, financial assistance, clinical research, innovation and advocacy, no kidney organization impacts more lives than AKF. AKF is one of the nation’s top-rated nonprofits, investing 97 cents of every donated dollar in programs, and holds the highest 4-Star rating from Charity Navigator and the Platinum Seal of Transparency from GuideStar. For more information, please visit KidneyFund.org, or connect with us on Facebook, Twitter, Instagram and LinkedIn. Contact Details American Kidney Fund Stefanie Tuck +1 202-470-1797 AKF@jpa.com Company Website https://www.kidneyfund.org/

November 19, 2021 11:53 AM Eastern Standard Time

Variational AI Secures $US3.5 Million in Seed Funding to Apply State-of-the-Art AI Platform to Generate Novel Small Molecule Therapeutics for Drug Development

Variational AI

Variational AI, developer of state-of-the-art generative AI technology to redefine the economics of drug development by accelerating the discovery of novel and optimized small molecules, today announced that it has raised $US3.5 million ($CDN4.3 million) in seed funding. The investment round was led by Flying Fish Ventures, Alliance of Angels and A&E Investments, with participation from Lip-Bu Tan and Amarjit Gill, Silicon Valley entrepreneurs, investors and advisors. Variational AI’s Enki algorithm learns from a training set of molecules screened against drug targets from both experimental and computational sources and then generates novel molecular structures with multiple pre-defined parameters/properties optimized to avoid common causes of drug attrition. This optimization is performed in parallel and can deliver results in months versus years and requires significantly less data than competing AI offerings. “The pandemic has demonstrated the importance of accelerating drug discovery and reducing the cost and risk to developing therapeutics,” said Frank Chang managing partner, Flying Fish. “We are thrilled to invest in Variational AI’s machine learning approach to discovering new molecules, which has the potential to dramatically impact the biopharma industry.” The seed funding will enable Variational AI to accelerate existing discovery programs for COVID-19, cancer and other disease areas. The company will also utilize the new capital to hire additional leaders in medicinal chemistry, cheminformatics, and machine learning, and recruit a Scientific Advisory Board. “The Variational AI team is excited to welcome our investors in sharing our vision for redefining the economics of drug development,” said Handol Kim, co-founder and CEO, Variational AI. “We look forward to accelerating our current programs and identifying new drug targets that Enki is uniquely suited to tackle to rapidly address unmet medical needs.” About Variational AI Variational AI uses state-of-the-art machine learning in a data-efficient method to rapidly generate novel and diverse compounds that are optimized for multiple properties to avoid the most common causes of drug attrition and increase clinical probability of success. Variational AI works with leading biopharmaceutical partners and is developing its own internal pipeline. To learn more, visit https://variational.ai. Contact Details Sage Morander +1 401-490-9700 variationalai@svmpr.com Company Website https://variational.ai/

November 17, 2021 10:15 AM Eastern Standard Time

ATAP ACTION NETWORK PHYSICIANS & PATIENT ADVOCATES MEET WITH CONGRESSIONAL OFFICES

Alliance for Transparent & Affordable Prescriptions

Today, physician and patient advocates on behalf of the Alliance for Transparent and Affordable Prescriptions (ATAP) Action Network (AN) will meet virtually with congressional lawmakers’ offices as part of its 2021 Capitol Hill Day. In these meetings, ATAP member organizations are advocating for lowering prescription drug prices for their patients by bringing accountability to the pharmacy benefit manager (PBM) industry. ATAP is an active advocate for patients in federal and state battles to amplify the voices of patients and physicians – especially as it relates to exposing PBM abuses and the impact on access to therapies (medications) needed for the treatment of patients. In the meetings today, ATAP AN will speak to congressional offices about three pieces of legislation, including: the PBM Accountability Study Act (H.R. 1829/S. 298), the Drug Price Transparency Act (S. 1523), and the Prescription Pricing for the People Act (S. 1388). “We are proud to bring policymakers the voices of patients and providers, two groups grossly underrepresented in the drug pricing debate’” said Dr. Robert Levin, the President of ATAP. “These voices from our members, combined with supporting advocacy organizations, and individuals fearing drug cost affordability, will surely inspire national leaders to take action to fix problems created by the PBM industry.” ATAP AN will meet with congressional member offices from Florida, Wisconsin, New York, Virginia, North Carolina, Missouri, Maryland, and California. Michael Schweitz, President of ATAP Action Network and Member of the Florida Society of Rheumatology, stated, “Officials in Washington understand that our members, those on the front lines of medical care, offer a valuable perspective. We see the struggles and confusion that patients are put through by this completely unnecessary middleman industry. We appreciate to opportunity to share these experiences and help more legislators see the light – and shine it on the PBMs.” Several ATAP member organizations are participating in meetings including, the American College of Rheumatology, the Coalition of State Rheumatology Organizations, Lupus and Allied Diseases Association, Inc., and many others. Kathleen A. Arntsen President & CEO of Lupus and Allied Diseases Association, (an ATAP member organization) stated, "As a patient-led organization representing those facing serious health conditions, we have direct experience with the frustration in struggling to access affordable and appropriate treatments due to PBM interference. We are thrilled to have the opportunity to share this information with elected officials and are hopeful that they will stand with patients and support fair drug pricing legislation that holds the PBM industry accountable." “PBMs generate significant profits while patients struggle to afford the cost of care,” said Steven Newmark, Director of Policy at the Global Healthy Living Foundation (an ATAP member organization). “We will show elected officials and policymakers what is really happening in exam rooms, and the stress patients experience due to PBM interference. There is a better way.” Updates from the meetings will be shared at https://atapadvocates.com/ and on Twitter with the hashtag, #ATAPHillDay21. About ATAP ATAP was created in 2017 with a mission to address prescription drugs costs and patient access to affordable treatment by regulating PBM practices and reforming the drug industry through educational outreach and grassroots advocacy initiatives at both the state and federal levels. Driven by the reality that many patients struggle to afford their medications, the physician and patient advocacy organizations joined to shine a light on the abusive practices of PBMs. ### To schedule an interview with an ATAP spokesperson please contact Dan Rene of kglobal at 202-329-8357. Please visit http://www.atapadvocates.com ATAP's mission is to address prescription drugs costs and patient access to affordable treatment by regulating PBM practices and reforming the drug industry through educational outreach and grassroots advocacy initiatives at both the state and federal level. Contact Details Dan Rene +1 202-329-8357 daniel.rene@kglobal.com Company Website http://www.atapadvocates.com

November 16, 2021 10:58 AM Eastern Standard Time

AppYea takes steps for Future Growth

Appyea

Provides the following letter to its shareholders from its Chairman Boris Molchadsky: "I am pleased with the progress AppYea/SleepX has been making this year. As part of the long terms objective, AppYea Inc. (OTCPINK: APYP) took the initial step to advance the prospects of the Company. As disclosed in our quarterly report yesterday to the OTC for the recently completed fiscal quarter, the reverse stock split, for which we are awaiting FINRA approval, is a proactive measure that we believe will better position us for success, and ultimately generate value for all of the Company’s stockholders. The ultimate aim is to raise our stock’s visibility within the investment community by improving long-term liquidity and creating a trading environment attractive to institutional investors in the hopes of broadening our shareholders. We are confident of the prospects of the anticipated commercialization of the SleepX DreamIT X3 in 2022". Mr. Molchadsky continued: “In conjunction with the corporate actions, AppYea has secured funding sources who we believe will asist the Company to restructure prior highly dilutive debt and providing the necessary capital to enable the Company to move forward on several fronts, including: 1. Closing of the merger between AppYea and SleepX—we are awaiting the required necessary regulatory approvals. 2. Completion of development and commencement of manufacturing the first product for snoring treatment. SleepX intends to start a pilot in December with a leading hardware manufacturer after withstanding the Company's endurance tests. 3. Preparation for starting clinical trials of the product for the treatment of Sleep Apnea. 4. Locating and acquiring synergetic technologies and broadening products variety in the sleeping and respiration field. Looking ahead, the primary focus of the Company is to ensure the long-term success of the Company by acting in the best interest of all of our shareholders. Thank you for your continued support and patience”. Legal Notice Regarding Forward-Looking Statements This release includes forward-looking statements. Such statements involve risks and uncertainties which could cause actual results to differ materially from those set forth herein. No statement herein should be considered an offer or a solicitation of an offer for the purchase or sale of any securities. Although APYP believes that the expectations reflected in the forward-looking statements and the assumptions upon which they are based are reasonable, it can give no assurance that such expectations and assumptions will prove to have been correct. Forward-looking statements, which involve assumptions and describe our future plans, strategies, and expectations, are generally identifiable by use of the words "may," "will," "should," "could," "expect," "anticipate," "estimate," "believe," "intend," or "project" or the negative of these words or other variations on these words or comparable terminology. The reader is cautioned not to put undue reliance on these forward-looking statements, as these statements are subject to numerous factors and uncertainties, including but not limited to adverse economic conditions, intense competition, entry of new competitors and products, adverse federal, state and local government regulation, inadequate capital, unexpected costs and operating deficits, increases in general and administrative costs, unanticipated losses, financial condition and stock price, inability to carry out research, development and commercialization plans and other specific risks. APYP does not undertake any obligation to publicly update any forward-looking statement. Neither APYP nor SLEEPX are subject to the reporting requirements of the Securities and Exchange Commission under the Securities and Exchange Act of 1934 as amended. Contact Details AppYea Inc. Asaf Porat info@appyea.com Company Website http://www.appyea.com

November 16, 2021 09:09 AM Eastern Standard Time

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New Options to Treat Alcohol Use Disorder

YourUpdateTV

Nearly 15 million Americans have alcohol use disorder and 75 million engaged in binge drinking or heavy alcohol use in the month before a survey conducted by the National Institute of Alcohol Abuse and Alcoholism. This problem has not been solved…yet. Hope for a solution is one of the big stories coming out of the Wonderland Conference, the largest psychedelic business event, ever. YourUpdateTV spoke with Awakn Life Sciences CEO, Anthony Tennyson who discussed the problem. “Alcohol addiction is a chronic disease effecting many millions of Americans each year. The success rates for treatments are typically quite low though. Three out of four people are back drinking alcohol within 12 months of seeking treatment. There is, however, a new hope. Psychedelic assisted therapy has been proven to be more effective at treating alcohol addiction than any other currently available treatment.” Awakn Life Sciences Corp. (NEO: AWKN) (OTCQB: AWKNF) (FSE: 954) (‘Awakn’), a biotechnology company developing and delivering psychedelic therapeutics (medicines and therapies) to treat addiction, recently announced that the ‘Ketamine in the Reduction of Alcoholic Relapse’ (KARE) psychotherapy intervention study, which was the first controlled study in the world to investigate ketamine-assisted psychotherapy, will be published in the American Journal of Psychiatry later this year. Professor David Nutt, former Clinical Director of the US National Institute of Alcohol Abuse and Alcoholism and currently Clinical Director at Awakn commented. The approach we’re taking is to use new medicines to disrupt the brains processes of addiction to allow people to escape from the repetitive cravings and which tie them to the alcohol and and also with therapy to help them plot a new path in their lives. About Awakn Life Sciences Corp.: Awakn Life Sciences is a biotechnology company with clinical operations, developing and delivering psychedelic therapeutics (medicines and therapies) to better treat addiction. Awakn’s team consists of world leading chemists, scientists, psychiatrists, and psychologists who are developing and advancing the next generation of psychedelic drugs, therapies, and enabling technologies to treat addiction. Awakn will deliver this evidence backed psychedelic therapies in clinics in the UK and Europe and through licensing partnerships globally. About YourUpdateTV: YourUpdateTV is a social media video portal for organizations to share their content. It includes separate channels for Health and Wellness, Lifestyle, Media and Entertainment, Money and Finance, Social Responsibility, Sports and Technology. Contact Details YourUpdateTV +1 212-736-2727 yourupdatetv@gmail.com

November 15, 2021 07:11 PM Eastern Standard Time

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Connecticut chooses BioTrack as the state's cannabis seed-to-sale tracking software

Forian

Forian Inc. (NASDAQ: FORA), a provider of technology, analytics and data science driven solutions for the healthcare and cannabis industries, announced that Connecticut has chosen BioTrack as the track and trace system for the state’s Department of Consumer Protection Drug Control Division. The state plans to use the BioTrack inventory tracking system to monitor the movement of cannabis products in the state’s medical and adult-use cannabis markets, while providing a real-time inventory of cannabis products available in the state and preventing unlawful diversion of products. The BioTrack software, commonly referred to as seed-to-sale tracking, will track cannabis from when it is first planted as a seed to the point of sale to the consumer. All licensed medical marijuana and adult-use cannabis establishments will be required to participate in the tracking system and log the movement of cannabis as it is grown, manufactured into other products, packaged, tested, and sold to qualifying patients or consumers. BioTrack’s state traceability system will also help recall cannabis plants and products deemed as unsafe/adulterated, and prevent adulterated and regulated materials from reaching the black market. “Connecticut has shown their desire to be at the forefront of cannabis by looking for best-in-class software solutions. We are very excited to work with the state to develop new technologies to support their cannabis-related initiatives,” said Moe Afaneh, VP of BioTrack. BioTrack’s point-of-sale software is used by customers in 38 states and 10 countries, while 10 state governments, including Connecticut, currently use BioTrack's patient portal and traceability system. About Forian Forian Inc. provides a unique suite of SaaS solutions, data management capabilities and proprietary data and analytics to optimize and measure operational, clinical and financial performance for customers within the traditional and emerging life sciences, healthcare payer and provider segments, as well as cannabis dispensaries, manufacturers, cultivators and regulators. For more information, please visit the Company's website at www.forian.com. Cautionary Statements Regarding Forward-Looking Statements This release contains "forward-looking statements" within the meaning of the federal securities laws, including Section 27A of the Securities Act and Section 21E of the Securities Exchange Act of 1934, as amended. In this context, forward-looking statements often address expected future business and financial performance and financial condition, and often contain words such as "expect," "anticipate," "intend," "plan," "believe," "seek," "see," "will," "would," "target," similar expressions and variations or negatives of these words. Forward-looking statements by their nature address matters that involve risks and uncertainties, many of which are beyond the control of Forian, and are not guarantees of future results, such as statements about the anticipated benefits of the business combination transaction involving Forian, Medical Outcomes Research Analytics, LLC and Helix Technologies, Inc., future financial and operating results, company strategy and intended product offerings and market positioning. These and other forward-looking statements are not guarantees of future results and are subject to risks, uncertainties and assumptions that could cause actual results to differ materially from those expressed in any forward-looking statements. Accordingly, there are or will be important factors that could cause actual results to differ materially from those indicated in such statements and, therefore, you should not place undue reliance on any such statements and caution must be exercised in relying on forward-looking statements. Factors that could cause actual results to differ include, but are not limited to, those risks and uncertainties associated with: the impact of the COVID-19 pandemic on Forian's business, operations, strategy and goals; Forian's ability to execute on its strategy; the timing of the introduction of new product offerings; and the additional risks and uncertainties set forth more fully under the caption "Risk Factors" in Forian's Annual Report on Form 10-K for the year ended December 31, 2020, as filed with the SEC on March 31, 2021, and elsewhere in Forian's filings and reports with the SEC. Forward-looking statements contained in this announcement are made as of the date hereof, and Forian undertakes no duty to publicly update or revise any forward-looking statements, whether as a result of new information, future events or otherwise, except as may be required under applicable law. ABOUT FORIAN Forian provides a unique suite of SaaS solutions, data management capabilities and proprietary data and analytics to optimize and measure operational, clinical and financial performance for customers within the traditional and emerging life sciences, healthcare payer and provider segments, as well as cannabis dispensaries, manufacturers, cultivators and regulators. For more information, please visit the Company's website at www.forian.com. Contact Details Forian Investors ir@forian.com Company Website https://forian.com/

November 15, 2021 02:43 PM Eastern Standard Time

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