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2022 Was A Year Of Growth, Funding, And Positive Results For BioRestorative Therapies

BioRestorative Therapies, Inc.

By Faith Ashmore, Benzinga BioRestorative Therapies Inc. (NASDAQ: BRTX) (“BioRestorative”) may have had a successful year of novel drug development. The company is engaged in developing therapeutic products using cell and tissue protocols, primarily with adult stem cells, for large multi-billion dollar markets that are underserved and affect millions of Americans, like chronic lower back pain and metabolic disorders. BioRestorative currently has two major programs that are being evaluated for a variety of chronic diseases and pain. Their novel drug BRTX-100 is an autologous stem cell product; the cells are harvested, cultured and then injected directly into the patient’s body. BioRestorative’s other product — ThermoStem® — has shown promising results in preclinical models for the treatment of obesity and related metabolic diseases. In December, BioRestorative was awarded a Small Business Innovation Research (SBIR) grant. This grant was given for the development and evaluation of the company’s ThermoStem program for developing a therapeutic to treat polycystic ovary syndrome (PCOS). Previously, the company was granted a Small Business Technology Transfer (STTR) grant for Phase 1 development of BRTX-100 to explore the therapeutic effects of PEG-peptide hydrogel-encapsulated hypoxic bone marrow stem cells. It’s rare that a company of its size has received two government grants, validating its technology and potential application. The company entered into an agreement with Regenexx, LLC, providing BioRestorative with the exclusive worldwide commercial rights of the intellectual property that is underlying some key principles of BRTX-100. Currently, BRTX-100 is in a Phase 2 trial with approximately 15 sites in the U.S. This exclusive arrangement should provide value to BRTX and or a commercial partner in potential later-stage development transactions. BRTX-100 began Phase 2 trials in February, defined as a prospective, randomized, double-blinded controlled study to evaluate the efficacy and safety of BRTX from a single injected dose. One of the company’s significant developments in 2022 was the completion of a cGMP manufacturing facility with an ISO 7-certified clean room. This facility was completed in April and was instrumental in progressing the company forward to meet the needs of Phase 2 clinical trials for chronic lumbar disc disease. Throughout the year, BioRestorative participated in several high-profile conferences. The company presented at H.C. Wainwright Bioconnect, Roth Inaugural Healthcare Conference and Dawson James Securities Conference, to name a few. BioRestorative was also granted a patent application for their ThermoStem program in Japan, which demonstrates the company’s potential for global application of their therapeutic products. BioRestorative and other companies like Lineage Cell Therapeutics Inc (NYSE: LCTX), Brainstorm Cell Therapeutics Inc (NASDAQ: BCLI), Vericel Corp (NASDAQ: VCEL) and large cap pharma as well such as Novo Nordisk (NYSE: NVO) and Pfizer Inc. (NYSE: PFE) are leading the charge towards a new era of medical advancement. As biotech companies become increasingly successful at providing therapeutic solutions, it will be interesting to see how technology and innovation leads to higher quality of life for patients who have previously been left with little or no solutions. To learn more about BioRestorative, visit its website. This article was originally published on Benzinga here. BioRestorative Therapies was founded by scientists and researchers committed to developing stem cell therapies to address unmet needs in patients with highly prevalent conditions.Our advances in stem cell biology and delivery protocols harbor great promise in conditioning our bodies’ own regenerative potential to treat major diseases more effectively than current interventions.Today, BioRestorative is actively developing programs that aim to dramatically increase quality of care for both (i) chronic back pain caused by disc degeneration, as well as (ii) metabolic disorders including obesity and diabetes. This post contains sponsored advertising content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Investor Relations ir@biorestorative.com Company Website https://www.biorestorative.com/

January 26, 2023 08:30 AM Eastern Standard Time

1606 Corp Now Trading under Ticker CBDW, Management Announces First Acquisition

1606 Corp

McapMediaWire -- 1606 Corp (OTC: CBDW ), an acquisition-based CBD product distribution company, announced that the company has successfully started trading on the OTC Market under the Ticker Symbol of CBDW. 1606 Corp’s S-1 registration statement became effective on January 22, 2022 and began trading on the OTC Market on January 17th, 2023. CBDW is a ticker symbol that embodies the business model of 1606 Corp and highlights management's goal to build a product-driven CBD-Wellness company. CBD.Inc and 1606 Corp. look to accumulate a diverse portfolio of CBD products and companies nationwide. The business model will achieve management goals by consolidating the fragmented CBD industry via acquisitions. The Ticker symbol CBDW will provide market recognition of these goals and the company's business model. "It’s always been a critical component of trading on the public markets for companies to utilize a stock symbol that reinforces the mission of the company. We purposefully requested the ticker symbol "CBDW" because that ticker represents us as a business. Our core focus is on buying companies with great wellness products and brands that embody the benefits of CBD, and the ticker says all of that in just four letters." said Greg Lambrecht, CEO, and Chairman of 1606 Corp. 1606 Corp (OTC: CBDW) has signed a letter of intent (LOI) to purchase 51% of Brio Nutrition’s ( https://brionutrition.com / ), a profitable CBD development and distribution company. Brio Nutrition's has agreed to an LOI with 1606 Corp and filed for an audit on September 30th, 2022, which is still pending. Upon completion of the audit, a combination of stock and cash, totaling USD 600,000.00, will be transferred, and the transaction will be complete. Brio Nutrition Revenue (unaudited) 2021 $763,079 2020 $1,116,336 "Brio Nutrition's is the first of many acquisitions we intend on closing this year. The CBD market is quite fragmented and growing so we're on a mission to consolidate the industry by purchasing companies with strong product brands and established distribution. We'll use these accumulated outlets to cross-pollinate our product line. It's going to be the key to our success" Said Greg Lambrecht CEO of 1606 Corp DBA CBD Inc. About Brio Nutrition; Brio Nutrition is a premium CBD product developer, supplier, and wellness company focused on providing the highest quality hemp derivatives and formulations for people and pets. Brio Nutrition develops and supplies CBD gummies, topicals, capsules, topicals and oils to assist.in treating pain, anxiety, sleep performance, and depression for all those in need. The products developed and distributed by Brio provide holistic solutions designed to ensure a higher quality of life for all living beings. About 1606 Corporation Management; Greg Lambrecht has successfully taken three companies public. He is starting with premium cigars International which went to the NASDAQ in 1997. Again in 2011, Mr. Lambrecht took Singlepoint public on the OTC Markets. Singlepoint is pursuing a move up the NASDAQ as well. He will take the knowledge and expertise learned in both these endeavors into the new public entity 1606 Corp. About 1606 Corp; In April 2021, 1606 Corp. was spun off from Singlepoint Inc. (OTCQB: SING).1606 has been able to develop smokable hemp brands to add to 1606 original, including Truz and CBD Singlez ( www.1606hemp.com ) The company intends to acquire Companies in the CBD, including brands, distribution, retail outlets, and manufacturing. 1606 Corp. was awarded the ticker symbol CBDW on January 12th, 2022. Industry Information; The Cannabidiol (CBD) market accounted for USD 12.8 billion in 2021 and is estimated to grow with a 21.7% CAGR between 2022 and 2028, according to Grand view research (link). The global cannabidiol (CBD) market size was valued at $5.18 billion in 2021 and is expected to expand, at a compounded annual growth rate (CAGR) of 16.8% from 2022 to 2030. Cannabidiol (CBD) is a chemical compound that is found in the cannabis Sativa plant, and is extracted from hemp or cannabis, generally from hemp due to its naturally high cannabidiol (CBD) content.. Forward-Looking Statements This press release contains statements that constitute forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. These statements appear in a number of places in this release and include all statements that are not statements of historical fact regarding the intent, belief, or current expectations of 1606 Corp (the "Company"), its directors, or its officers with respect to, among other things: (i) financing plans; (ii) trends affecting its financial condition or results of operations; (iii) growth strategy and operating strategy. The words "may," "would," "will," "expect," "estimate," "can," "believe," "potential" and similar expressions and variations thereof are intended to identify forward-looking statements. Investors are cautioned that any such forward-looking statements are not guarantees of future performance and involve risks and uncertainties, many of which are beyond the Company's ability to control, and actual results may differ materially from those projected in the forward-looking statements as a result of various factors. You should not place undue reliance on forward-looking statements since they involve known and unknown risks, uncertainties, and other factors, which are, in some cases, beyond the Company's control and which could, and likely will materially affect actual results, levels of activity, performance, or achievements. The Company assumes no obligation to publicly update or revise these forward-looking statements for any reason, or to update the reasons actual results could differ materially from those anticipated in these forward-looking statements, even if new information becomes available in the future. Important factors that could cause actual results to differ materially from the company's expectations include, but are not limited to, those factors that are disclosed under the heading "Risk Factors" and elsewhere in documents filed by the company from time to time with the United States Securities and Exchange Commission and other regulatory authorities. Contact: Greg Lambrecht greg@1606corp.com CBD.inc Austen Lambrecht austen@1606corp.com CBD.inc 888-223-9510 Company Websites; www.1606hemp.com www.CBD.Inc Contact Details Greg Lambrecht greg@1606corp.com Austen Lambrecht austen@1606corp.com

January 26, 2023 08:00 AM Eastern Standard Time

Spectral MD "very excited" about 2023

Spectral MD Holdings Ltd

Spectral MD Holdings Ltd (AIM:SMD) chief operating officer Niko Pagoulatos speaks to Proactive's Thomas Warner about his plans for the company during 2023. He reveals more details about the timeline for the DeepView Wound Imaging System and explains what milestones investors can expect, adding that he is "very excited" about what the year has in store. Contact Details Proactive Proactive UK Ltd +44 20 7989 0813 uk@proactiveinvestors.com