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Neuroinflammation A Key Indicator For Alzheimer’s, But Current Treatments Show Little Success In Reducing Or Even Increase It — Could This Rising Company Have The Answer?

Benzinga

By David Willey, Benzinga There have been several accelerated approvals granted to treatments for patients with Alzheimer’s disease (AD) by the Food and Drug Administration (FDA) in recent months, and there are several treatments also in development. Tiziana Life Sciences (NASDAQ: TLSA), a biotechnology company with a robust pipeline of therapies, is looking to bring a novel therapy to market that would tackle neuroinflammation in patients with AD. In 2021, the FDA granted accelerated approval to Aducanumab, developed by Biogen Inc. (NASDAQ: BIIB), and early in 2023, it gave accelerated approval to Lecanemab, developed by Eisai Co Ltd (TYO: 4523) and Biogen. Both immunotherapies target the disease pathology by reducing amyloid plaque buildup in the brain. While Lecanemab does slow the rate of cognitive decline, it includes the risk of adverse events, and Aducanumab was denied authorization by the European Medical Agency, partly because of fears of side effects like swelling in the brain. A couple of other treatments are currently in development for treating AD, including Eli Lilly’s (NYSE: LLY) Donanemab, which expects a decision from the FDA by the end of the year, and Acumen Pharmaceuticals’ (NASDAQ: ABOS) ACU193, which has announced safety and efficacy results from its phase 1 trial. Tiziana Focusing On Neuroinflammation For AD While these drugs target amyloid, none of them are focused on reducing neural inflammation. However, neuroinflammation is a key indicator for AD, caused by microglia – the primary immune cells of the brain – that are activated by the buildup of amyloid plaque. Targeting neuroinflammation has the potential to be a successful therapeutic strategy for tackling mild to moderate AD. An investigational new drug (IND) application has filed for Foralumab, a treatment that dampens neuroinflammation by binding to T-cells. “There are no FDA-approved treatments for Alzheimer’s disease specific to the neuroinflammation caused by microglia activation triggered by amyloid beta plaque,” said Matthew W. Davis, the Chief Medical Officer of Tiziana. “We plan to study 3-months administration of intranasal foralumab in Alzheimer’s disease patients to see if neuroinflammatory activated microglia will return to the baseline homeostatic state.” The company has already seen positive results with foralumab in a trial for indications against multiple sclerosis. Because this drug has already undergone a phase 1 trial, Tiziana may now potentially be able to fast-track foralumab as a treatment for AD. It has applied for a $3 million grant from a prestigious Alzheimer’s research foundation to support a potential phase 2a trial. If it is granted approval, Tiziana’s drug could provide a novel treatment for patients with mild to moderate AD. The Alzheimer's therapeutics market was worth $5 billion in 2022 and is expected to reach $18 billion by 2029, at a compound annual growth rate (CAGR) of 19% over 2022-2029. Click here to learn more about Tiziana and its pipeline of treatments on its website. This post contains sponsored content. This content is for informational purposes only and not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

July 27, 2023 09:00 AM Eastern Daylight Time

Bluepeak Internet Ranks First in Communities in Wyoming, Oklahoma, North Dakota, South Dakota and Minnesota

Bluepeak

Bluepeak internet service is ranked number one for fastest internet speeds, most consistent network and lowest latency in several markets in its service area. That’s the conclusion of Ookla’s newly released SpeedtestTM Market Index report for the second quarter of 2023, including data collected from millions of consumer-initiated tests across the country. The report – which ranks mobile and fixed broadband speeds from internet service providers around the world monthly – shows that Bluepeak is ranked highest for delivering the fastest median download and upload speeds, most consistent network and lowest latency to its internet customers in several different places during the second quarter of 2023.* The achievements for each market where Bluepeak service received a top ranking, verified by Ookla®, are as follows: Wyoming The fastest download and upload speeds, most consistent network and the lowest latency in all of Wyoming. The fastest download and upload speeds and most consistent network in Cheyenne and Laramie County. The fastest download and upload speeds, most consistent network and the lowest latency in Laramie. The fastest download and upload speeds in Casper and Natrona County. Oklahoma The fastest download and upload speeds and most consistent network in Stillwater and Payne County. The fastest download and upload speeds in Lawton. The fastest download and upload speeds in Altus. The fastest download and upload speeds in Bartlesville and Washington County. North Dakota The fastest download and upload speeds and most consistent network in Grand Forks and Grand Forks County. South Dakota The fastest upload speeds in Springdale Township. The fastest upload speeds in Madison and Lake County. Minnesota The fastest upload speeds in Marshall. As a result of Bluepeak’s competitive service, residents of these communities benefit from greater choice among their internet options. Research shows, greater competition for consumer goods – like internet – benefits consumers by lowering prices, boosting investment and enabling innovation. In addition, a 2020 report by Federal Reserve Bank of Richmond on “Bringing Broadband to Rural America” determined that broadband access and adoption are linked to increased job and population growth, higher rates of new business formation, higher home values, and lower unemployment rates. Ookla® is the global leader in network intelligence and connectivity insights. Over eighteen million tests are actively initiated by consumers each day across all Speedtest platforms, with over 45 billion tests completed to date. As a result, Ookla has the most comprehensive analytics on worldwide internet performance and accessibility. For more information on Bluepeak, visit mybluepeak.com. *Based on analysis by Ookla® of Speedtest Intelligence® data for median download speeds, upload speeds and consistency score, and multi-server latency, in the identified geographies, U.S., Q2 2023. About Bluepeak Bluepeak is building a faster, more reliable internet without the things that get in the way of great service - like red tape, hidden fees, and slow response times. Offering up to 5 gigabits of speed for residential customers and 10 gigabits for businesses, Bluepeak is a whole new ballgame - from internet to TV, to connecting every device in a home, to powering a business, Bluepeak not only provides the best fiber connections in the communities it serves, but also meets the growing needs for how its customers live. Contact Details Bluepeak Jesse Granger +1 720-703-4315 jesse.granger@mybluepeak.com Company Website https://www.mybluepeak.com

July 26, 2023 09:23 AM Mountain Daylight Time

PBX Pickleball partners with Zinc Agency to Provide the Ultimate Corporate Pickleball Experiences with Retired Professional Athletes

PBX Pickleball

PBX Pickleball, a new organization that unites the pickleball community with retired professional athletes, announced a partnership with Zinc Agency to lead the planning and implementation for customized corporate experiences centered around the game of pickleball. Zinc becomes the official corporate sales and hospitality partner of PBX Corporate Experiences, which is one of four platforms of PBX Pickleball that will feature top retired professional athletes from all major sports, including baseball, hockey, football, and basketball. “Through PBX Pickleball, we plan to create the ultimate pickleball experience and provide a new client entertainment platform for business leaders to participate with their clients and prospects alongside professional retired athletes,” said Gary Rosenberg, Chief Revenue Officer at Zinc Agency. “Golf has always been considered the ‘sport of business,’ but we see pickleball opening up a new channel for client engagement and relationship building.” Zinc Agency has over 25 years of experience creating customized corporate events across various lifestyle categories. The company is known for leveraging professional talent to curate customized private experiences with professional athletes, chefs, speakers, musicians, illusionists, and other entertainers. “As the fastest growing sport in America that anyone can play, pickleball is the perfect activity for businesses to leverage for entertainment, networking, and team building outside of boardrooms and video calls,” said Jason Clement, CEO of The Sports Facilities Companies, the parent company for PBX Pickleball. “Zinc Agency has a successful track record of selling corporate experiences across various sports and entertainment categories. When we add the element of retired pro athletes as PBX Pros, we thought Zinc was the ideal partner to create that ultimate experience.” PBX Pickleball consists of four experiences: PBX Tour brings together retired sports stars turned avid pickleball players, starting with athletes who previously competed at the highest levels of their sports. Each player represents their respective sports in PBX Pickleball tournaments for audiences watching in person, via television broadcasts, and through digital media. PBX Pro-Ams allow amateur pickleball players to play with and against former male and female stars of major sports teams. PBX Pickleball Pro-Ams align with professional pickleball tour stops and occur adjacent to these events, including the PBX Tour. PBX Dream Weekends offer the ultimate pickleball experience for amateur participants. Pickleball enthusiasts can learn from professional pickleball players and interact with dozens of retired athletes. PBX Corporate Experiences are fully customizable with turnkey services to support corporate meetings, incentives, conferences, and exhibitions. Your employees, partners and prospects can play pickleball with retired professional athletes. Since forming in June 2023, PBX Pickleball has also confirmed partnerships with the Major League Baseball Players Alumni Association (MLBPAA) and the NHL Alumni Association. About PBX Pickleball PBX Pickleball creates memorable experiences by uniting well-known retired professional athletes with amateur pickleball players and fans. Established in 2023, PBX Pickleball consists of four experiences: the PBX Tour, PBX Pro-Ams, PBX Dream Weekends, and PBX Corporate Experiences. The company is part of The Sports Facilities Companies (SFC), the nation’s leading resource for the management and development of sports, recreation, wellness, and events facilities. To learn more about PBX Pickleball, go to https://pbxpickleball.com or follow @pbxpickleball on Instagram, Facebook, Twitter, and LinkedIn. About Zinc Agency Zinc is an agency focused on curating creative, one-of-a-kind experiences that leverage the power of talent in sports, music, fashion, the culinary world, theater, and any of life’s other passions. Zinc’s approach is to always deliver a truly memorable experience that allows our clients to build and strengthen relationships with their customers. Zinc works hard to conceptualize unique themes, whether attached to a specific personality or aligned with a major event. From there, Zinc ensures all the details are flawlessly executed with a turnkey approach to event management. In addition to client entertainment, Zinc delivers entertainment solutions for corporate retreats, conferences and sales incentive trips. For more information, go to www.zincagency.com. Contact Details Eric Nemeth nemeth@ericpr.com Company Website https://www.pbxpickleball.com/

July 26, 2023 09:15 AM Eastern Daylight Time

Locality Appoints Michael Mayer as Chief Product Officer

Locality

Locality, the industry’s preeminent local television solutions provider, today announces the appointment of Michael Mayer as Chief Product Officer. Mayer brings 25+ years experience in building ad platforms and in driving the industry forward through his work in streaming, broadcast, and cable to his new role. He will report to Keith Kazerman, President of Streaming and Ann Hailer, President of Broadcast at Locality. Mayer joins Locality following his involvement as a founding member of the leadership team at Peacock, where he helped form the team and launch the product, steering NBCU into streaming. Prior to this role, Mayer spent seven years within NBCU Ad Sales, building the Ad Sales Platform which unified media selling across broadcast and digital platforms. Throughout his 25+ year career, Mayer has proven himself to be a leader in helping organizations transform and succeed. Mayer's experience will be instrumental in reshaping the ways Locality enables brands to form meaningful connections with local audiences at scale. “Here at Locality, we are dedicated to increasing collaboration across broadcast and streaming” said Kazerman. “Mike’s expertise in building teams, streamlining processes, and delivering innovative solutions will help deliver transformative results, meet our customers' evolving needs, and ultimately drive more dollars to local video. His strong relationships with leading industry partners, and systems experience to know where to build and where to buy will be key in Locality’s continued growth.” "We believe in empowering our team with the best talent, and Michael Mayer's addition reinforces this commitment. With his vast experience in building ad platforms and transforming organizations, we look forward to his leadership in shaping a game-changing go-to-market strategy for local television. We are actively investing in product and technology to build a converged future, and Michael's appointment aligns with this mission,” said Hailer. “I’m thrilled to be joining the Locality team to lead on product strategy, innovation, and development,” said Mayer. “I believe in Locality’s goal of creating seamless processes between broadcast and streaming and look forward to working with the team to develop simplified solutions to drive growth.” Locality is the industry’s preeminent local television solutions provider, committed to addressing the evolving needs of advertisers by unlocking the power of local and driving dollars to the local video marketplace. Formed through the union of CoxReps and Gamut, Locality brings together the best talent in both broadcast and streaming. With more than 11 locations in the US, Locality helps brands tap into the mindset of the local consumer and precisely reach optimal markets, nationally. Having served more than 1,500 ad agencies and 4,500 advertisers, to date, Locality offers the best premium inventory that the industry has to offer to help brands optimize their spend and target audiences at scale. For more information, please visit www.locality.com. Contact Details Kite Hill PR Kerriann Becker kerriann@kitehillpr.com

July 26, 2023 09:07 AM Eastern Daylight Time

AI Singapore Awards S$20M in Research Funds to Address Challenges Relating to Increase Use of AI in Emerging Apps

AI Singapore

SINGAPORE - Media OutReach - 26 July 2023 - AI Singapore (AISG) announced today that it will award up to S$20 million, through the Robust AI Grand Challenge and the AI for Materials Discovery Grand Challenge, to support five multidisciplinary teams which will address challenges related to the increasing use of AI in emerging applications. AISG launched both Grand Challenges in December 2022 in collaboration with the Future Systems and Technology Directorate (FSTD), MINDEF Singapore, and DSO National Laboratories (DSO). Each Challenge is a first-of-its-kind and represents a major milestone in research collaboration between the academia and defence ecosystems. The research outcomes will have the potential for dual-use applications and can be leveraged by both the industry and defence to benefit Singapore. The grant awards were presented by Mr Heng Chee How, Senior Minister of State for Defence at the Joint Grant Awards Ceremony. In his speech, Mr Heng said, "The advancement of Artificial Intelligence (AI) will open up new possibilities and MINDEF/SAF is poised to harness its power to build important capabilities for our future. MINDEF's approach is to collaborate extensively with local and global partners from research institutes, and institutes of higher learning and industry. MINDEF's Defence Technology Community, which designs and develops technological capabilities for the SAF, will play a key role in this effort. "Moving forward, we will also be expanding our partnerships with industry, to accelerate progress in developing AI technologies and applications. I encourage the various communities to come together to co-ideate and co-innovate. I would like to invite all researchers and practitioners with bold ideas to reach out to us. Together, let's collaborate, innovate and build an exciting and better future, he added." Professor Mohan Kankanhalli, Deputy Executive Chairman for AISG, said that the current development efforts and outcomes can be translated into better and safer technologies for everyday living. "The problems that are being addressed have dual-use applications and can be leveraged by both industry and defence ecosystems to benefit Singapore. We are excited to work with our valued collaborators, FSTD and DSO, as they have deep expertise in both grand challenges to advise, guide and empower our research teams to develop novel AI solutions that can effectively address important problems faced by Singapore and the world. We believe that there is potential for these technologies to be scaled globally in the future". Robust AI and AI for Materials Discovery Grand Challenges AISG's Grand Challenge programme takes an outcome-driven approach to solve important problems faced by Singapore and the world through multidisciplinary collaboration and translation of AI-based solutions from research to deployment. Researchers from local Institutes of Higher Learning (IHLs) and Research Institutes (RIs), along with their collaborators from the public and/or private sectors, were invited to propose ground-breaking research ideas that adopt AI techniques to address both Grand Challenges' statements. Each challenge statement was jointly defined by AISG, DSO and FSTD. Robust AI Grand Challenge - "How can we design robust CV systems for AVs that can recover at least 80% of their original accuracy after physical testing-time adversarial attacks?" Computer vision (CV) systems based on AI/ML are vulnerable to adversarial attacks which could compromise their safety and security, thus limiting their performance and adoption in critical environments. In the field of autonomous vehicles (AV), these could result in delays, accidents and potentially, even death. This Grand Challenge aims to encourage the development of innovative approaches that increase the robustness of these CV systems, to accelerate the adoption of CV systems in critical environments. AI for Materials Discovery Grand Challenge - "How can AI accelerate inverse material design to discover advanced materials that are 50% lighter while retaining and/or enhancing their functional properties?" Technological breakthroughs and the development of next-generation systems such as lightweight transportation vehicles and energy-efficient buildings are often underpinned by the discovery and development of new and advanced materials. However, this discovery process can be prohibitively long and expensive. In addition, conventional methods can be limited by a scientist's personal experience, knowledge and even biases, resulting in only incremental discoveries. This Grand Challenge aims to advance the state-of-the-art applications of AI in materials discovery, to develop solutions that can help scientists accelerate material discovery process and overcome the constraints of conventional methods. This would in turn enable them to keep pace with the increasing demand for new and advanced materials for next-gen systems. AISG received 16 (7 Robust AI; 9 AI for Materials Discovery) quality research proposals from multidisciplinary teams in response to both grant calls. The teams comprise lead Principal Investigators (PIs) and Co-PIs from the National University of Singapore (NUS), Nanyang Technological University (NTU), Agency for Science, Technology and Research (A*STAR), Singapore Management University (SMU), Singapore University of Technology and Design (SUTD) and Singapore Institute of Technology (SIT). They also involve industry partners and/or collaborators from overseas universities. An Evaluation Committee comprising members from various stakeholders in the AI ecosystem selected five projects to be awarded Stage 1 funding: Robust AI Grand Challenge Holistic Moving Target Defence for Autonomous Driving Perception (by Associate Professor Rui Tan, NTU) - This project will develop a Moving Target Defence (MTD) approach that creates and deploys AI mechanisms that are diverse and rapidly changing to limit the exposure of vulnerabilities and opportunities for attacks, increase the complexity and cost for attackers. Development of Stable Robust and Secure Intelligent Systems for Autonomous Vehicles (by Professor Shuzhi Sam Ge, NUS) - This project will harness the collective strengths of machine learning, stable control and generative AI to develop a robust and intelligent system that can adjust its neural network's behaviour and characteristics in real- time to counter adversarial attacks in complex environments. Towards Building Unified Autonomous Vehicle Scene Representation for Physical AV Adversarial Attacks and Visual Robustness Enhancement (by Professor Yang Liu, NTU) - This project will develop novel multi-view and multi-modal defences based on a unified framework that comprises a novel AV scene representation that will be used to generate realistic scenes with diverse conditions and attack vectors. The projects are expected to deliver suites of multi-modal attack and defence techniques that can be deployed in the real world to increase the robustness of AI models applied in multi-sensor CV systems. AI for Materials Discovery Grand Challenge MATAI: An AI-Powered Generalist Material Discovery Platform (by Professor Bo An, NTU) - This project will develop an AI-powered generalist platform with three key components: a holistic material database, a foundational material property predictor and a generalist multi-property material designer in a large search space. Design Beyond What You Know: Material Informed Differential Generative AI (MIDGAI) for Light-Weight High-Entropy Alloys and Multi-functional Composites (by Professor Ivor Tsang, A*STAR) - This project will develop a generative AI framework for materials design that combines with discriminative models to enhance robustness and overcome data scarcity. By incorporating domain knowledge, the AI model will enable a more controllable, directed, and efficient exploration of material design spaces through advanced optimisation algorithms. The projects are expected to deliver AI solutions that can be used by AI and materials researchers to (i) discover novel materials based on performance needs, (ii) efficiently explore beyond the boundaries of conventional methods, (iii) exploit new and existing scientific knowledge and (iv) reduce resource and time cost of material discovery cycles. In Stage 1, the teams will be awarded up to S$4M each to work on their project for the next three years. Funding support for Stage 2 will be determined as part of the final evaluation near the end of Stage 1. Selected teams could be funded up to S$5M over 2 years where the teams will have the opportunity to work with agencies to adapt and scale up the developed AI techniques for dual-use applications. About AI Singapore AI Singapore (AISG) is a national programme launched by the National Research Foundation (NRF) to catalyse, synergise and boost Singapore's artificial intelligence (AI) capabilities to power our future, digital economy.AISG will also bring together all Singapore-based research institutions and the vibrant ecosystem of AI start-ups and companies developing AI products, to perform use-inspired research, grow the knowledge, create the tools, and develop the talent to power Singapore's AI efforts.AISG is driven by a government-wide partnership comprising NRF, Smart Nation and Digital Government Office (SNDGO), Infocomm Media Development Authority (IMDA), Economic Development Board (EDB), Enterprise Singapore (ESG), amongst others. Contact Details Communications Consultant Joseph Rajendran +65 9228 7801 joseph@wiredcomms.sg Company Website https://aisingapore.org/

July 26, 2023 09:00 AM Eastern Daylight Time

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Media OutReach Newswire Launches Industry-First Press Release Distribution Campaign Intelligence Report

Media OutReach Newswire

HONG KONG SAR - Media OutReach - 25 July 2023 - Media OutReach Newswire, Asia's first global newswire, has launched the next-generation SaaS integrated communications portal that offers three simple steps in press release submission, centralised post-release reports and a groundbreaking Press Release Distribution Campaign Intelligence Report that provides holistic insights of press release distribution campaign performance for the first time in the newswire industry. With proprietary technology at its core, the Press Release Distribution Campaign Intelligence Report gives PR professionals a full and complete view of press release campaign performance over customised period. One of the challenges faced by PR professionals is reporting the performance of their press release distribution campaign to stakeholders and C-Suite executives. As a newswire focused on providing solutions to the PR industry, Media OutReach Newswire's intelligence report measures the performance of press release distribution by evaluating interactions between journalists and the press release. Developed in-house by Media OutReach Newswire's team of programmers and UX designers, the innovative solution sets a new standard in the PR industry for monitoring and measuring the impact and effectiveness of clients' press release distribution campaign and the return on their investment. "Our intelligence reports enable PR professionals to gain insights into how many publications have covered their story and what are the top publications reading their releases," Jennifer Kok, Founder and CEO of Media OutReach Newswire, says. "This intelligence provides PR professionals with the information they need to identify the media that is supporting their brand, and which are not. With this intelligence, PR professionals can now work with clarity in planning their communications campaign to reach their targeted list of media." PR professionals can generate an intelligence report by selecting a customised period and exporting it to PowerPoint in ready-to-use reporting format. This marks the turning point in how the PR industry reports with intelligence, speed and efficiency. "Our Press Release Distribution Campaign Intelligence Reports focuses on the true needs of PR professionals and will advance the value of public relations in the communications industry," Kok says. "This intelligence report will fundamentally reshape how agencies and communications professionals gain insights into the effectiveness of their campaign in reaching their target journalists and media through write-up by journalists and know exactly which media is following their company news as well as their PR campaign performance over time." Kok says Media OutReach Newswire continues to set new industry standards and lead innovation in the newswire industry. The launch cements Media OutReach Newswire's position as Asia Pacific region's leading global press release distribution service dedicated to innovation and solving challenges faced by the public relations industry. Penn Leung, Director at Creative Consulting Group, a PR consultancy which has partnered with Media OutReach Newswire since 2016, says the new intelligence service will transform how they plan and report the effectiveness of the press release distribution campaign to clients. "By offering holistic insights into the performance of our press release distribution campaign allows us to have a more meaningful and strategic conversation with the C-Suite about the impact and value of their investment into public relations," Leung says. "With this new intelligence report offered by Media OutReach Newswire, we can now tabulate multi-release performance in a timely and cost-effective way, thus enhancing the speed and quality of deliverable reports to our clients." Since 2009, Media OutReach Newswire has been the voice of Asian companies, helping them to build their global brand reputation in global markets from Canada, the USA, UK, Europe such as Germany, France, Italy, Spain, across the Middle East such as United Arab Emirates, Saudi Arabia, Africa and Latin America such as Brazil, Argentina, plus Southeast Asia markets such as Thailand, Vietnam, Singapore, Malaysia, Indonesia and the Philippines, plus China, Hong Kong, Japan, South Korea, Australia, New Zealand and countries in the Belt and Road Initiative. Media OutReach Newswire's global press release distribution network offers an authentic service that connects clients to journalists to optimise write-ups, build media relations, post their news on real media sites and reach investors. For financial news release, Media OutReach Newswire will post their clients press release in English and with options in Traditional and Simplified Chinese into all the world's leading financial and international news services such as Bloomberg, Refinitiv Eikon, Refinitiv Middle East – Zawya, Dow Jones Newswire, Factset, Infront, Morningstar, Reuters News Agency, Associated Press (AP) and Agence France Presse (AFP). About Media OutReach Newswire Founded in 2009, Media OutReach is the first global newswire founded in the Asia-Pacific region with offices in Singapore, Malaysia, Vietnam, Japan, Mainland China, Hong Kong, Thailand and Taiwan. Media OutReach is the only press release newswire that owns its distribution network of more than 140,000 journalists, 400 trade categories, 65,000 media titles and 600 media partnerships spanning 26 countries across the APAC region. As an integrated communications solution, Media OutReach is redefining press release distribution. With proprietary technology at its core, Media OutReach Newswire distributes multi-language and multimedia press release content directly to the inboxes of targeted editors and journalists to optimise news write-ups, build media relations and automate the reporting process with key performance metrics. Its pioneering post-release reports give detailed insights into how journalists access your press release by publication and by country. Connect with us: LinkedIn: linkedin.com/company/media-outreach-li/mycompany/ Twitter: twitter.com/mor_asia Facebook: facebook.com/MediaOutReachHK/ Contact Details Director Marketing Communications Matt Eaton +852 3594 6640 matt.eaton@media-outreach.com

July 25, 2023 11:00 AM Eastern Daylight Time

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Next Generation DFS Platform GameBlazers Signs New Partnerships with Full Moon Sports Solutions and Raging Moose

GameBlazers

GameBlazers, a sports gaming platform empowering sports fans to create and manage their own experience, today announced the company signed partnerships with two industry-leading and best-in-class consulting companies, Full Moon Sports Solutions and Raging Moose. Both companies will help accelerate GameBlazers’ business objectives as it brings its revolutionary product to the Beta Test phase and eventual launch. Full Moon Sports Solutions is a strategy consulting firm specializing in business and product development for the fantasy, gaming and sports betting industry. Full Moon is aiding in developing strategic partnerships and licensing opportunities with professional sports leagues and associations. Raging Moose is a technology consulting group specializing in game design and gameplay mechanics. The group is assisting GameBlazers in developing a proprietary Item Distribution Framework that assigns the Athletes, Multipliers, Rarities and other forms of metadata, to the in-game Items. The firm has experience working on FIFA Ultimate Team, as well as other major video games with similar mechanics to those on the GameBlazers platform. “In any start-up environment, surrounding yourself with the smartest minds in the industry and creating a network of strategic partnerships is the cornerstone for success,” said Rourke Sturthers, CEO of GameBlazers. “GameBlazers is unlike anything the daily fantasy market has seen, so bringing in Full Moon Sports Solutions and Raging Moose was paramount to making sure our vision for the platform was met. From both companies’ previous work, we know that GameBlazers will bridge the gap between the modern and future worlds of fantasy sports, and live up to its unique user experience.” GameBlazers is set to launch before the 2023 football season. For updates and information about the platform, check out GameBlazers.com. About GameBlazers GameBlazers is a new sports gaming platform bridging the gap between the digital and physical worlds into a first-of-its-kind user experience. GameBlazers blends the best elements of fantasy sports, sports gaming, and collectible in-game items to create a more sustainable and more engaging gameplay. GameBlazers enables innovative gameplay mechanics that give Players the opportunity to be the Owner, GM and Coach of their Fantasy Franchise. For more information or to join the beta, please visit: https://www.gameblazers.com/ Contact Details Sterling Randle srandle@hotpaperlantern.com Company Website https://www.gameblazers.com/

July 25, 2023 10:01 AM Eastern Daylight Time

Minuteman Press Franchise Owners Jim and Seamus Mooney Celebrate 5 Years and Relocation to Clark, NJ with Grand Opening Event

Minuteman Press International Inc

Jim and Seamus Mooney have a lot to celebrate lately. The father-son team behind the Minuteman Press franchise in Clark, NJ (formerly Westfield) held their Grand Opening Palooza Event on June 22, 2023 as they celebrated their relocation to Clark as well as 5 years in business. Minuteman Press in Clark is located at 1120 Raritan Road, Suite 2, Clark NJ 07066. The grand opening event for Minuteman Press in Clark, NJ was sponsored by the Irish Business Association and featured live music, food trucks, vendors, and more. The Irish Business Association also recently honored Minuteman Press in Clark by awarding Jim and Seamus their Company of the Year Award. In addition, Jim and Seamus continue to hit new monthly sales milestones for their business. On the relocation, Jim shares, “We opened our doors on June 1, 2018. We have been in business for 5 years and we were looking for a larger production facility. Today, Minuteman Press Clark is a full-service printing, mail-house, and marketing design firm. We specialize in apparel (screen printing and embroidery), signage, paper based products (booklets, brochures, letterhead, envelopes, etc.) promotional products, mailings and graphic design.” Over the past 5 years, Jim has helped grow the family business through networking with a heavy focus on community involvement. He is President and an active member of Greater Westfield Area Chamber of Commerce, which includes multiple towns in Union County. Jim also appreciates being able to put his own stamp on Clark, Westfield and the surrounding community through his business. On that note, Jim says, “We have a lot of pride when we see our work displayed or distributed in the community – storefronts, window signage, direct mail, brochures, business cards – it’s always great to get kudos from happy clients.” Jim’s professional background includes managing strategic marketing for multi-unit franchise brands across various industries, most notably, McDonald’s Corporation working on the Company and Ad Agency side of the QSR industry. Jim says, “As the majority of my career was spent in franchise marketing, I am a true believer in franchising. Because I worked in advertising agencies where we had production and graphic design capabilities; I was very comfortable buying this business.” Jim continues, “I look at Minuteman Press as an ad agency for other businesses in Clark and Westfield and the surrounding towns. My career skills match up really well with what we are doing, and I am proud of our capabilities as well as the infrastructure we have in place being part of the Minuteman Press franchise family.” Speaking of family, while Jim concentrates on marketing the business, his son Seamus handles the operations. Prior to Minuteman Press, Seamus worked in recruiting and education operations management. Jim says, “Seamus is fantastic as our Vice President of Operations and I couldn’t do this without him. We’re a good team because we complement each other’s skills.” What’s it like going to work every day as a father and son? “It's an opportunity most people don't get to have,” Seamus Mooney said. “It's been great getting to work together for over five years — I've learned a lot during this time about business and life. Having a family business is rewarding." “It is fantastic to work with my son Seamus and to see him grow strategically and operationally as our vice president of operations,” Jim Mooney added. “Seamus is also a great thought partner in the business. It is a unique and fun experience.” Minuteman Press in Clark, NJ is located at at 1120 Raritan Road, Suite 2, Clark NJ 07066. For more information, call 908-857-4644 or visit their website: https://minuteman.com/us/locations/nj/clark/ Learn more about #1 rated Minuteman Press franchise opportunities and read Minuteman Press franchise reviews at https://minutemanpressfranchise.com Contact Details Minuteman Press International Chris Biscuiti +1 631-249-1370 cbiscuiti@mpihq.com Company Website https://minutemanpressfranchise.com

July 25, 2023 10:00 AM Eastern Daylight Time

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Cue Health’s Growing Integrated Care Platform Of Lab-Quality Diagnostic Tests For Use At-Home And At The Point-of-Care Is Transforming How Healthcare Is Delivered

Benzinga

By Rachael Green, Benzinga Last month, the Food and Drug Administration (FDA) granted a landmark De Novo authorization for Cue Health’s (NASDAQ: HLTH) at-home COVID-19 test that delivers lab-quality results within 20 minutes. The move makes Cue Health the first company to receive De Novo authorization for an at-home molecular test for any respiratory disease. With a growing portfolio of at-home tests for a range of infectious diseases, the recent FDA authorization is the latest milestone for the San Diego-based healthcare technology company that is transforming the diagnostics space. Having already generated over $1 billion of revenue from its molecular COVID-19 test previously under FDA emergency use authorization (EUA) in 2021 and 2022 combined, the De Novo is a full authorization and allows Cue Health to continue to provide accurate testing at-home and at the point-of-care into the future. Cue’s Scalable Platform Can Meet the Needs of a $180 Billion Diagnostics Market The global diagnostics market was valued at approximately $180 billion in 2022 and is projected to grow to over $348 billion by 2030. Some of the key drivers of that growth are molecular diagnostics and the at-home testing and point-of-care segments where Cue Health is focused. Molecular diagnostics analyzes DNA or RNA, and have traditionally been conducted in a lab, such as PCR testing. While antigen and lab-based PCR testing are both still common, convenient at-home and point-of-care molecular diagnostics have implications across the industry and are competing as alternative diagnostic solutions — playing an important role in infectious disease testing as they yield results that are both accurate and fast. During the pandemic, the use of telehealth and virtual care for diagnosis spiked to 69% of all doctor-patient visits. However, the broader need for and power of telehealth to improve outcomes and lives is still in high demand. Especially in diagnostics, the current system can often be inconvenient, inefficient, expensive, and disconnected. Cue is out to change that — the company reduces the duration of time between testing and receiving actionable health information from 1-14 days to under an hour. That seamless process eliminates much of the inefficiencies in the current standard approach to healthcare delivery. Cue Health is fixing this point of friction for both patients and providers. The company’s mission is to empower people to live their healthiest lives, and that starts with enabling access to health information and actions that are personalized and proactive anywhere and at any time. The healthcare technology company’s diagnostic solutions for use at-home and at the point-of-care deliver results in ~20 minutes with lab-quality accuracy. Its COVID-19 test that just received De Novo authorization demonstrated overall accuracy of 98%. If the test results are positive, users can consult a licensed clinician through the Cue Health App to discuss treatment options and get prescribed medications, if appropriate, delivered to their door that same day. Cue’s platform has also become highly valuable for healthcare providers and the company has stated that “point-of-care is the largest near-term opportunity for Cue’s differentiated offering,” with strategic expansion into medical facilities and offices around the nation representing a massive market. Cue’s accurate, fast, and reliable results make the easy-to-use test a convenient, cost-effective option for diagnosing patients at the office. Instead of waiting to follow up with patients after lab results come in, healthcare providers can get lab-quality results in minutes and identify the best treatment options for that patient that very day. Cue Health’s Diagnostics Menu Continues To Expand In addition to the COVID-19 test, Cue Health has received emergency use authorization (EUA) for the Cue Mpox (Monkeypox) Molecular Test for any CLIA-waived facility, and has submitted an EUA application for a flu-and-COVID-19 multiplex test, and De Novo requests for a standalone flu test and a respiratory syncytial virus (RSV) test. All of these would run on the same easy-to-use Cue Reader and feature seamless connectivity to the Cue Health App so that customers can go from diagnosis to treatment within the same day. Cue’s Expanded Product Offering Beyond Molecular Diagnostics The company’s overarching goal is to put people in greater control of their health. With this at the heart of what Cue does, it also added a suite of at-home screening and diagnostics kits in March that allow customers to mail samples for processing in a lab to complement its diagnostic testing strategy. The mail-in kits include panels for markers of heart, liver, or kidney health as well as colon cancer screening and comprehensive sexual health panels for men and women. The company continues to add tests and treatments to its pharmacy offering for other common health and wellness conditions, such as hair loss and erectile dysfunction, among others. Its existing portfolio has already helped the company see its revenue more than double since its initial public offering (IPO) at the end of 2021, although testing volume has slowed with the decreasing COVID-19 prevalence in recent months. This could put the company in a strong position as it awaits decisions on pending EUA applications and De Novo requests and prepares two additional submissions for a strep throat test and a chlamydia/gonorrhea test that are compatible with the Cue Reader. Those submissions are slated for the second half of 2023 — with significant investments in R&D and infrastructure behind them and expected to pay off. This post contains sponsored content. This content is for informational purposes only and not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

July 25, 2023 09:25 AM Eastern Daylight Time

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