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How Canoo's Flexible, Award-Winning Electric Vans Are Helping Reshape Commercial And Government Fleets

Benzinga

By Meg Flippin, Benzinga Learn more about Canoo Inc. by checking out its Investor Relations Website. From delivery vans that have driver-side storage, built-in removal tools and hanging storage to pickup trucks with fold-down workspaces, hidden storage and expandable cargo space, Canoo Inc. (NASDAQ: GOEV) is reimagining the transportation market with its suite of fully-electric lifestyle delivery vehicles (LDVs) and democratized battery power solutions. Justin, Texas-based Canoo (with its main manufacturing in Oklahoma City and battery module manufacturing in Pryor, Oklahoma) is bringing electric vehicles, namely delivery vehicles in the Class 1 and 2 categories, to large commercial and government fleets via a proprietary modular electric platform designed to maximize vehicle interior space, enabling it to be customizable across owners and applications. The company offers a lineup of electric delivery vehicles targeting smaller more flexible uses, including last mile delivery. EVs With A Twist Take Canoo’s LDV190 for starters. The newest to the Canoo lineup, the LDV 190 is a long-haul delivery vehicle that gets more than 200 miles per charge. But the range and horsepower aren’t what makes the LDV190 and its other EVs different. It’s the flexibility and space within the vehicle where the company says things get interesting. Canoo’s delivery vehicles are built on a modular platform allowing customizable configurations whether you are hauling large packages or racks of clothing. Foldable and retractable storage and tables on the exterior of the vehicles make Canoo’s vehicles unique in the market, the company says. It also sticks to a clean, minimalist shape that has received design award recognition, most recently several Red Dot Design Awards. The Red Dot Award is an annual international competition recognizing excellence in design and among the world’s largest design competitions. Canoo’s steer-by-wire technology is not common in vehicles today. Canoo says using steer-by-wire technology reduces moving parts and cabin intrusion, resulting in more usable interior space, better driver ergonomics and the addition of a panoramic window to improve road visibility. This type of technology has been used in aviation for decades, but Canoo is the first to bring it to a production vehicle. The LDV190 offers multiple cargo configurations including shelves and racks, and advanced safety features such as blind spot monitoring and traction stability control. Canoo is going after the delivery market with this electric LDV and counts the U.S. Post Office (USPS) as a customer. Canoo has already delivered six right-hand drive versions of the LDV 190 to the USPS as part of its move to electrify and modernize the postal service’s delivery fleet, and it will likely run another RFP for vehicles later this year where Canoo will compete. The USPS is investing $40 billion to upgrade and improve the organization’s processing, transportation and delivery networks. Success With Walmart And Other Last Mile Delivery Companies The LDV130 is another electric lifestyle delivery vehicle in Canoo’s lineup. This one is more compact and is designed for the worker and last-mile deliveries. Go2 Delivery, a logistics solutions provider with a sustainability mission, recently signed a definitive agreement to purchase five LDV130s with the potential to purchase up to an additional 85 vans. Go2 Delivery will integrate Canoo’s LDV130 into its delivery fleet to enhance operational efficiency, provide eco-friendly deliveries for customers and lower its environmental impact, Canoo said. Canoo’s LDVs have been in deep testing with the e-commerce operation of Walmart Inc. (NYSE: WMT) which inked a deal with Canoo a couple of years ago to purchase 4,500 LDVs. Walmart has an option to buy up to 10,000. Canoo is part of Walmart’s plan to achieve zero emissions by 2040, the companies said when announcing the deal. Consumers aren’t forgotten in Canoo’s lineup. The LV is Canoo’s minivan of sorts. It includes Canoo’s steer-by-wire system, a wide field of view, a panoramic sunroof and five- and seven-seat configurations. This variant was customized and sold to NASA as the Crew Transportation Vehicles (CTVs) that will take the Artemis Mission astronauts to the launchpad and has effectively replaced the NASA Astrovan. The Canoo Pickup and American Bulldog were designed for everything and came with built-in draws, foldable tables, modular storage and a pull-out bed extension. A version of the pickup, the Screaming Eagle, was sold to the U.S. Army for testing for their Light Tactical Vehicle (LTV) program. Canoo’s line-up of fully electric LDVs is designed to usher in a new era of sustainability for the commercial transportation market. Taking a page from Tesla (NASDAQ: TSLA), Canoo is betting the modular design and the ability to customize the cargo space on the fly will appeal to companies and government customers looking to lower their carbon footprint. Keep a look out for more Canoo Inc. announcements here. Featured photo by Canoo. Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders. This post contains sponsored content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

September 24, 2024 08:30 AM Eastern Daylight Time

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Xtreme Trucking Selects HOPTEK’s Dispatch Engine® Solution for Real-Time Visibility and Optimization of Fleet Operations

Hoptek

HOPTEK, a global leader in AI-driven trucking and fleet transportation solutions, has been selected by Xtreme Trucking of Wisconsin, one of the U.S.’s leading technology-first transportation and logistics providers, for its Dispatch Engine® solution, a digital platform providing instant visibility and access to the spot load market, while matching available carrier capacity across thousands of possible options. HOPTEK’s “digital twin” will provide real-time visibility and enable Xtreme to boost operational efficiency and fleet utilization, while reducing driver turnover and deadhead miles, resulting in material cost savings and profitability. Started as a small independent operation in 2006, Xtreme Trucking was formally established in 2009 to become a quality diversified transportation provider, with a growing revenue profile and extensive coverage across the United States. Through HOPTEK’s Dispatch Engine®, Xtreme has leveraged real-time data visibility and dynamic decision-making to drive operational velocity to achieve up to a 20% increase in both Revenue per Hour and Weekly Revenue Miles per Driver – a clear competitive advantage. Travis Nelson, President and Founder of Xtreme Trucking said: “Between supply chain complications, market shifts, and driver shortages, the past several years have been a rollercoaster ride for our industry. Selecting HOPTEK’s Dispatch Engine solution addresses several seemingly intractable challenges, enabling us to optimize fleet utilization, increase driver satisfaction, and reduce deadhead empty miles. HOPTEK’s robust visibility platform enables us to make the best available decision, even as fleets remain dynamic, and routing and load scenarios shift constantly. We at Xtreme immediately recognized the value of HOPTEK’s strategic offering to our operation and how it would support the achievement of our goals.” Transportation and logistics are the backbone of the U.S. economy. Xtreme fuels that economic growth by delivering best-in-class operations, innovative technology solutions, and a talented workforce. The company was seeking a solution that would address very specific issues related to driver miles, route efficiency, and utilization in one platform. Achieving these goals required a unique set of capabilities. HOPTEK’s Dispatch Engine® solution closes these gaps by creating dispatchable recommendations that consider the entire fleet, at any given moment. It gets critical information to dispatchers, planners, drivers, and other stakeholders in near real-time, supercharging efficiencies and profitability. Balaji Guntur, CEO and Co-founder of HOPTEK said: “We’re excited and honored to have been selected as a long-term partner to Xtreme Trucking. Their keen eye for innovative technologies and solutions that genuinely add measurable value attests to why the industry will view Xtreme as a trend setter and leader in small to mid-size fleet tech adoption. We believe they have selected a solution that will enable them to achieve their technology goals, while at the same time supporting their efficiency mindset and profitability targets.” —Ends— About Xtreme Xtreme Trucking LLC delivers superior reefer transportation and dedicated services across the United States. With a leading view on technology and a modern truck and trailer fleet, we are an essential solutions provider for customers who value the integrity of their supply chain and require safe, and exceptional service. Moreover, Xtreme strives for leading on-time delivery and customer service, and as a technologically minded fleet, and remains deeply committed to promoting both customer and driver satisfaction. To find out how Xtreme Trucking Delivers, please visit: https://www.xtremetrucking.com/ About Kearney Kearney is a leading global management consulting firm. For nearly 100 years, we have been the trusted advisor to C-suites, government bodies, and nonprofit organizations. Our people make us who we are. Driven to be the difference between a big idea and making it happen, we help our clients break through. For more information, please visit: https://www.kearney.com/ About HOPTEK HOPTEK was founded in 2021 when global strategy and management consultancy Kearney brought its transportation and tech expertise together to help transform the trucking industry. After HOPTEK’s AI-powered system helped a leading U.S. fleet solve major operational challenges and drastically boost their performance, the company opened that technology to fleets across the U.S. With transformational technology tools such as Fleet Scanner®, Freight Finder®, and Dispatch Engine®, trucking and logistics companies can actively analyze fleet performance, identify and reduce wasteful wait times, and optimize dispatching in responsive real-time. For more information, please visit: https://www.HOPTEK.ai/ Contact Details Sean Maharaj Sean.Maharaj@hoptek.ai

September 23, 2024 09:00 AM Eastern Daylight Time

Luftgekühlt 10 celebrates Porsche Turbo Anniversary at Universal Studios Backlot

Luftgekuhlt

As the original Porsche icon, the 911 Turbo has become shorthand for high-performance and cutting edge technology. The cars have graced the bedroom wall of thousands of children around the world who grew up idolizing the signature flared fenders and Whale Tail spoiler. Fifty years later, the 930 model, introduced at the Paris Motor Show on October 3, 1974, not only established the 911 Turbo as a legendary vehicle but inserted its name into the vernacular. In recognition of the importance of the 911 Turbo and to celebrate its birthday, Luftgekühlt 10 will showcase a number of landmark vehicles, including a collection of original and modified examples in true Luft style within the Universal Studios Backlot. And in keeping with Luft tradition, the organizers have secured a number of significant racing examples, such as the 930-based Vasek Polak Racing Porsche 934, which claimed the 1976 Trans-Am Championship. Chassis #0179 will be on display; one of two cars entered that year by the California Porsche dealer. It was driven by George Follmer and Hurley Haywood. Throughout the season, Follmer predominantly raced #0174 until a heavy crash saw him swap to #0179. The 934 dominated the Championship, allowing Follmer to win the title with Haywood in second. The team switched to a 935 for the 1977 season. Luft 10 attendees will be able to enjoy the 911 Turbo exhibits as well as a plethora of significant air-cooled Porsches. We’ll reveal more featured cars in the weeks to come. SUPPORTING EVENTS A full itinerary was recently shared via the Luft newsletter, allowing fans to get their Luft fix in more ways than one. The fun starts on Thursday October 3 with the Luft pre-party at Gunther Werks in Huntington Beach, CA. It runs from 7-11pm and all are welcome. Don’t party all night because you won’t want to miss the Rise & Shine pre-party at Race Service on Venice Blvd in Los Angeles. It takes place on October 4 from 9am-12pm and there will be plenty of coffee available. You can then grab lunch before heading over to the Petersen Automotive Museum on Wilshire Blvd in Los Angeles to celebrate 50 years of the 911 Turbo with fellow enthusiasts. Cocktails and gourmet bites will be served but you’ll need tickets to attend, which are available from the Petersen HERE. The event takes place on Friday October 4 from 6-10pm. Following Luft 10 itself – which takes place on Saturday October 5 at the Universal Studios Backlot in Universal City – enthusiasts can join the Mobil 1 Air-Cooled Caravan on October 6. The rally is celebrating its fourth year with a quintessential Los Angeles rally drive. Registered participants will meet at Hansen Dam Recreation Center at 7am and will end at Porsche Santa Clarita with a Cars & Coffee-style event. Registration info will follow shortly. Porsche Santa Clarita is also hosting Porsche owners and enthusiasts at its Official After Luft Brunch on October 6 from 9am-12pm. Anybody wishing to join the event should please register at DOsorio@galpin.com. LUFT 10 TICKETS Although it’s only been a matter of weeks since tickets went on sale, the Early Access option has already sold out. Vehicle registration also closed once the show car capacity was reached. Fortunately, General Admission tickets are still available (at the time of writing) from luftgekuhlt.com/pages/luft-10. However, we’re duty-bound to remind enthusiasts that the last time we visited the Universal Studios Backlot for Luft 6, tickets sold out quickly and many people were disappointed. Don’t be that person who has to experience the event vicariously through other people’s Instagram accounts! SPONSORS Porsche Classic returns, staged in the iconic Gas Station at Universal Studios – the same location it occupied at Luft 6. The Porsche Classic team will globally launch ORIGINALE 10 to celebrate the tenth anniversary of Luft, along with a photo booth to commemorate your visit. Stop by to receive an exclusive wax-sealed event copy of ORIGINALE. Meguiar’s will be located next door in the Engine Company No. 2 Firehouse. The company will have its latest car care products on display, as well as some emergency supplies for owners of exhibition vehicles who forgot to bring detailer! Meguiar’s specialists will be on-hand to answer questions about the correct products to maintain, protect and restore every finish and material on your car to Reflect Your Passion. There will also be a curated display of modified 911 models for visitors to enjoy. Luftgekühlt is also excited to welcome Kinecta Credit Union to its anniversary event, marking the brand’s first appearance. A Southern California original, Kinecta has branches across Los Angeles, Orange, Ventura and Santa Barbara counties. The company is set to make a memorable debut by showcasing two legendary purple Porsches that are sure to captivate Luft fans. The Kinecta team will be located on New York Street, offering exclusive promotions and exciting merchandise. Keep an eye out for the signature Kinecta purple as they immerse themselves in the vibrant Porsche culture that defines Luftgekühlt. Don’t miss out on this exciting addition to the Luft family! EDITOR’S NOTE Images from Luftgekühlt 6 at Universal Studios Backlot are available here: dropbox.com/scl/fo/0febarq3oac99k05cau6i/AG4Tlv7pzV6i_sjLnv8v86w?rlkey=gn9xw9yjf8gz30jf0nqkm52sf&dl=0 A video is available to download and share here: youtu.be/_OM5NqrC3IQ Porsche 934 photos provided by Linhbergh Nguyen for 000 Magazine. ABOUT LUFTGEKÜHLT In the Porsche vernacular, Luftgekühlt represents all the air-cooled cars in the manufacturer’s history, from the Pre-A 356 through the 993 model line, which ended in 1998. A true Porsche happening, Luftgekühlt is an experiential car culture event centered around a tightly curated list of historically significant or interesting cars, both street and race. There is no set formula for our events, but we're excited by cool venues, fun people, and creative expression, so you can bet those elements will always be included. The team strives to develop wild ideas that celebrate the passion we have for all things air-cooled, including exciting collaborations with likeminded people and brands. For more information, visit luftgekuhlt.com Contact Details Media Contact media@luftgekuhlt.com Company Website https://luftgekuhlt.com/

September 19, 2024 06:28 AM Pacific Daylight Time

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New Horizon Aircraft (NASDAQ: HOVR) Poised For Growth With Hybrid Aircraft Technology Amid Small-Cap Strength

Benzinga

By Gerelyn Terzo, Benzinga The future has arrived, thanks to electric Vertical Take-Off and Landing (eVTOL) aircraft. eVTOLs are aircraft that launch vertically, similar to a helicopter, rather than a conventional takeoff. Hybrid-electric eVTOL designs have the potential to enable greater speed, range and cargo capacity than fully electric versions and could play an important role in the future of aviation. While eVTOL is still in its early days, with the industry currently in the testing phase, its value is predicted to surpass $30 billion by the next decade amid a CAGR of 15.3% since last year. And while Tesla (NASDAQ: TSLA) is playing a key role with electric vehicles, New Horizon Aircraft (NASDAQ: HOVR) hopes to take on a leadership position in the eVTOL aircraft market segment. Toronto-based New Horizon says it has been an early mover in eVTOL technology with its Cavorite X7 prototype aircraft, a hybrid model built for real-world use cases. Its aircraft takes off vertically, true to eVTOL form. However, once in flight, it reverts to the configuration of a conventional airplane, owing to the company’s patented HOVR wing system. The Cavorite X7 is built to reach speeds of 250 miles per hour, with a fuel capacity of more than 500 miles, making it appropriate for real-world applications like travel when the time comes. Learn more about New Horizon Aircraft’s technology here. New Horizon Puts Pedal To The Metal On eVTOL Aircraft Led by a team of operators, aviators and aerospace engineers, New Horizon has been going full throttle of late as it prepares to fully transition its large-scale prototype aircraft by the end of this year. Chief among New Horizon’s priorities is advancing the development of its hybrid-powered eVTOL aircraft. The company has been making strides from a technical standpoint while also building out its team internally. Flight test program: Among the technical highlights, New Horizon has published results on its flight test program, which it says are surpassing its expectations. The company has performed hundreds of flight tests and is nearing full transition speed, which it anticipates achieving by year-end. Full-scale aircraft development: New Horizon says it is innovating the proprietary patent technologies that are critical to its unique aircraft, including full-scale propulsion units that are essential to its HOVR wing technology. Cooling system and power tests for its full-scale propulsion units continue to unfold and it says the outcomes are positive so far. Encouraging test results extend to the company’s Cavorite X7’s patented HOVR wing design, which the company says enables safer, more durable performance even in the most forbidding conditions. Digital twin development: New Horizon harnesses a hardware-in-the-loop (HITL) digital twin technology to test its aircraft, supporting the rapid testing of large-scale prototype aircraft like the Cavorite X7. Its hybrid technology is fueled by its HOVR wing technology, allowing the aircraft to fly nearly all of its missions in a formation that closely resembles that of a conventional aircraft. Meanwhile, the company says the hybrid power system delivers greater range, speed and payloads in its class. When the Cavorite X7 reaches commercialization, New Horizon expects it to have the power to disrupt the travel industry with its speed, efficiency and cost savings over traditional aircraft. However, its potential use cases also extend to medical evacuation, critical supply delivery, disaster relief and special military missions. “Our unique, customer-first approach prioritizes building a tough eVTOL aircraft that can operate in bad weather, icing conditions and other challenging operational environments. This strategy is gaining strong traction with operators, driving substantial demand,” said Horizon Aircraft CEO Brandon Robinson. To keep pace with this ongoing innovation, New Horizon recently expanded its team with the addition of seasoned engineer Tom Brassington as Chief Technology Officer. New Horizon Says It Could Be Poised To Benefit From Possible Small-Cap Stock Demand Earlier this year, New Horizon made its debut in the publicly traded markets amid a business combination with special purpose acquisition company (SPAC) Pono Capital Three. Most recently, New Horizon returned to the equity capital markets with a $2.9 million public offering. The deal, the closing for which was announced in August, comprised 2.8 million Class A ordinary shares with various types of warrants. New Horizon’s timing is no coincidence, as the company says it could be poised to benefit from an expected ongoing rotation in the equity markets into small cap stocks. While small cap stocks have been gaining attention of late, New Horizon took matters into its own hands. It commissioned its own global poll of investment managers to uncover evidence of investor demand for small- and micro-cap names working with more sustainable technologies, where the upside potential is considered greater than larger companies because they are coming from a lower base. The aerospace company says it found that investor demand is in fact there, with more than three-quarters of survey participants demonstrating an expectation for exposure to these asset classes among institutional investors to increase in the next six to twelve months. Slightly more than one-third (34%) of them say allocations to these stocks could increase by at least 25%. Investors who are interested in participating in New Horizon’s growth story can learn more about this company’s financials here. Read more about New Horizon Aircraft: Pilotless Planes Are Coming, But Not Just Yet, Says New Horizon Aircraft CEO On The Horizon: How One Company Plans To Use Its Innovative Aircraft Design To Revolutionize Regional Air Travel From Stage To Stage: How New Horizon Aircraft's eVTOLs Could Simplify Tour Logistics For Taylor Swift Sustainably Featured photo by ELG21 on Pixabay Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders. This post contains sponsored content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

September 19, 2024 08:45 AM Eastern Daylight Time

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Industry Update: 3 Exciting Precision Oncology Players to Watch Following Summit’s Meteoric Rise: Silexion, Nuvectis, Scorpian

Global Markets News

Summit Therapeutics (NASDAQ: SMMT) recently captured headlines with the release of its Phase 3 data for ivonescimab, a targeted NSCLC therapy that has generated substantial buzz. The results from its trial conducted in China showed a dramatic 49% reduction in the risk of disease progression or death compared to Merck’s Keytruda, signaling a potentially disruptive force in NSCLC treatment. However, the news wasn’t without its concerns—since the trial data originates from China, there are questions about its applicability to broader, global populations. As noted by BMO Capital Markets’ Evan Seigerman: “Results may or may not be generalizable beyond the China-focused patient population initially assessed.” Despite this, Summit’s valuation has risen by over 100%, now approximating $19 billion. With such a high valuation, the company could see limited room for further significant gains, leading many in the industry to explore other emerging opportunities in precision oncology. Alongside Summit, there are quite a few other players in the field. Some if these companies have even already shown promising initial results and could see similar success in the future if they were to report positive results. These emerging players are worth watching for those interested in following precision oncology drug candidates and pipelines. Among them are precision oncology innovators such as Silexion Therapeutics, Nuvectis Pharma, and Scorpion Therapeutics, which we discuss below. Silexion Therapeutics: Disrupting the KRAS-Driven Cancer Space Silexion Therapeutics (NASDAQ: SLXN) is another under-the-radar player in the precision oncology space, with a focus on KRAS-driven cancers—a notoriously difficult target in oncology. While current small-molecule KRAS inhibitors are making progress, they are often limited to specific mutations, such as KRAS G12C, which accounts for a small percentage of cancers. Silexion’s RNA interference (RNAi) approach offers a broader solution, targeting a wider spectrum of KRAS mutations, particularly in pancreatic cancer, one of the deadliest and most treatment-resistant cancers. At the heart of Silexion’s approach is its LODER™ platform, which delivers siRNA directly to the tumor site, silencing KRAS mutations at the genetic level. This localized delivery not only increases efficacy by concentrating the treatment in the tumor, but it also reduces systemic side effects. Silexion’s next-generation candidate, SIL-204, is an optimized siRNA formulation designed to target pan-KRAS G12x mutations, positioning it to treat a broader range of KRAS-driven cancers beyond pancreatic cancer, such as lung and colorectal cancers. In Phase 2 trials for locally advanced pancreatic cancer, Silexion's LODER™ platform showed a 9.3-month improvement in overall survival when combined with standard chemotherapy. Additionally, the objective response rate (ORR) increased from 20% with chemotherapy alone to 55% with the combination, and in some cases, tumors that were initially non-resectable became operable after treatment with LODER™. These results are especially encouraging given the limited options available for pancreatic cancer patients. SIL-204, is expected to enter Phase 2/3 clinical trials in 2025-2026. What makes Silexion particularly intriguing is its current market valuation. Valued at aproximatly just ~$9 million following its SPAC merger, the company’s valuation could be perceived as low when compared to some of its peers, especially given its innovative technology and promising clinical achievements. Some have wondered whether this low valuation has more to do with dynamics post-SPAC companies. If Silexion can report positive results in its later-stage trials, the company’s outlook could dramatically improve, reflecting the potential of its RNAi-based platform. Like NXP900, SIL-204 could potentially have vast applications across multiple KRAS-driven cancer types, making Silexion a company to watch closely as it advances through clinical development. Nuvectis Pharma: Targeting NSCLC and Beyond by Inhibiting SRC/YES1 Kinases Nuvectis Pharma (NASDAQ: NVCT) has been quietly making strides in the precision oncology sector, developing innovative therapies aimed at overcoming treatment resistance in hard-to-treat cancers. Its lead candidate, NXP900, targets NSCLC by inhibiting the SRC/YES1 kinases, which play critical roles in cancer cell survival and resistance to current therapies. This approach positions NXP900 as a potential game-changer in the treatment of NSCLC, particularly in patients who have developed resistance to EGFR and ALK inhibitors, such as AstraZeneca’s Tagrisso and Novartis’ Alecensa. NXP900 is still in the early stages of clinical development, currently undergoing Phase 1 trials. However, preclinical studies have already shown that it has strong anti-tumor activity in resistant NSCLC models. Even more promising is its potential application beyond NSCLC. Like Summit's ivonescimab, NXP900 focuses on resistance, but it also has broader applications due to its ability to target multiple cancer types driven by SRC/YES1 pathways. This versatility makes it a promising asset not just for NSCLC but also for other difficult-to-treat cancers like squamous cell carcinomas. In addition to NXP900, Nuvectis is advancing NXP800, another precision oncology candidate that is further along in the clinical development process. NXP800 is currently in Phase 1b trials, targeting ARID1a-mutated cancers such as ovarian and endometrial cancers. The early clinical data for NXP800 is promising, showing positive responses in patients with platinum-resistant ovarian cancer. With two strong candidates in the pipeline, Nuvectis is positioning itself as a formidable player in the precision oncology landscape. As Summit’s ivonescimab continues to gain attention, Nuvectis’ earlier-stage NXP900, with its NSCLC focus and beyond, could see similar success in the future if clinical results continue to trend positively. Scorpion Therapeutics: Pioneering Mutant-Selective Therapies Scorpion Therapeutics is redefining the frontier of precision oncology with its focus on delivering highly selective small molecules targeting validated and previously undruggable cancer mutations. Its lead candidate, STX-478, is a mutant-selective, allosteric PI3Kα inhibitor currently in Phase 1/2 trials for advanced solid tumors. Early data presented at the ESMO Congress 2024 highlighted its potential, with STX-478 demonstrating a 23% overall response rate in breast cancer and a 21% response rate across all tumor types, positioning it as a potentially best-in-class PI3Kα inhibitor. STX-478 is notable for its ability to spare wild-type PI3Kα activity in normal tissues, avoiding the toxicities seen with previous PI3Kα inhibitors, such as hyperglycemia and rash. Tumor reductions were seen in 72% of patients treated with STX-478 as a monotherapy, with circulating tumor DNA levels dropping in 86% of patients. This mutant-selective precision could help overcome the limitations of existing PI3Kα inhibitors, which have struggled with dose-limiting toxicities. In July 2024, Scorpion raised $150 million in a Series C financing round, co-led by Frazier Life Sciences and Lightspeed Venture Partners. The additional funding will support the advancement of STX-478 and other pipeline assets, positioning Scorpion for further clinical success. Scorpion’s pipeline includes a broad range of wholly-owned compounds that target both validated and novel cancer targets, positioning the company for future expansion into larger patient populations. As STX-478 progresses through clinical development, Scorpion is poised to become a significant player in the precision oncology space, making it another company worth watching closely. Optimistic Outlook for Precision Oncology The precision oncology space is experiencing a golden era of innovation, with companies like Summit Therapeutics, Nuvectis Pharma, Silexion Therapeutics, and Scorpion Therapeutics leading the charge. As the focus shifts towards targeted therapies that address resistance mechanisms, the market is increasingly favoring companies with novel approaches and broad applications. Summit’s meteoric rise has shown that there is tremendous potential for companies that can demonstrate efficacy in overcoming cancer resistance. While Summit has already captured much of the current attention, companies like Nuvectis, Silexion, and Scorpion, with their earlier-stage pipelines, offer exciting opportunities for the industry to keep a close eye on. As these companies continue to report clinical data and advance through trials, the potential for breakthroughs in treating some of the most difficult cancers grows stronger. With targeted therapies offering the possibility of overcoming resistance without the need for chemotherapy, the future of cancer treatment looks brighter than ever. For those in the oncology space, keeping a close eye on emerging players like Nuvectis, Silexion, and Scorpion could lead to transformative developments as the field of precision oncology continues to evolve. * * * This update may include speculative forward looking statements. Readers are cautioned that any such forward-looking statements are not guarantees of future performance and involve risks and uncertainties, and that actual results may differ materially from those in the forward-looking statements as a result of various factors. the BioTech and Pharma industries are volatile and risky and readers are advised to seek out preffesional advice in the relevent feilds from licensed profesionals. This update is for informational purposes only and is not intended to serve as financial, investment or any form of professional advice, recommendation or endorsement. Please review the full documentation detailing financial compensation disclosures and disclaimers the article is subject to. [ https://justpaste.it/ch2qt/pdf ]. Global Markets News Network is a commercial digital brand compensated to provide coverage of news and developments related to innovative companies as detailed in the full documentation and it is thus subject to conflicts of interest. Contact Details News Coverage ronald@futuremarketsresearch.com

September 19, 2024 07:45 AM Eastern Daylight Time

Car Garage Expert Offers Reliable Roadside Assistance Services in Dubai

Rev Up Marketers

Car Garage Expert, a leading name in automotive repair and maintenance, is proud to announce its dependable services roadside assistance in Dubai. As a trusted and customer-centric car garage near me in Dubai, Car Garage Expert is committed to providing rapid and reliable services that ensure motorists are never left stranded on the roads. In the fast-paced environment of Dubai, drivers require quick and efficient solutions to sudden car troubles. Whether it's a flat tire, dead battery, engine breakdown, or even lockout situations, Car Garage Expert's well-equipped team is available 24/7 to address any emergency and get drivers back on the road swiftly. Our goal is to offer peace of mind to drivers across Dubai," said Muhammad Fahad Malik, CEO of Car Garage Expert. “We understand how frustrating unexpected breakdowns can be, which is why we’ve designed our roadside assistance services to be fast, reliable, and affordable. Our team is just a phone call away to ensure you’re never stuck for long.” Car Garage Expert’s state-of-the-art facility is also equipped to handle a wide range of repairs and maintenance, ensuring that drivers receive comprehensive automotive care. The garage's skilled technicians have vast experience working with all car models, making Car Garage Expert a top choice for as a trusted and customer-centric garage near me in Dubai. About Car Garage Expert: Car Garage Expert is a reputable automotive repair service provider in Dubai, offering a wide range of services including regular maintenance, engine repairs, transmission servicing, and roadside assistance. With a focus on quality, transparency, and customer satisfaction, the garage has built a solid reputation as a reliable garage near me in Dubai. Contact Details Car Garage Expert Mian Muhammad Fahad cargarageexpertdxb@gmail.com Company Website https://CarGarageExpert.com

September 17, 2024 09:21 AM Eastern Daylight Time

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Join Benchmark International's Exclusive Webinar "Seller Motivation: What Goes Into the Decision to Sell?"

Benchmark International

Are you considering selling your business? Deciding when and why to sell is one of the most significant decisions you’ll ever make as a business owner. While maximizing financial proceeds is often at the forefront of these decisions, it’s essential to recognize that it’s not the only factor. Life circumstances, time with family, and other qualitative considerations can often outweigh financial gain. To help you navigate this complex process, we invite you to join our upcoming webinar: Seller Motivation: What Goes Into The Decision To Sell? Space is filling up fast, so register today! Why You Should Register Selling a business is about more than just crunching the numbers. In this exclusive webinar, you’ll gain valuable insights into the full spectrum of motivations that drive business owners to sell. Understanding these motivations can help you make a well-rounded and informed decision about your business’s future. This webinar is a must-attend for business owners contemplating the sale of their business, particularly in today’s strong but disciplined market. By attending, you’ll be better equipped to evaluate both the financial and personal factors that play a crucial role in this life-changing decision. Whether you’re focused on securing a comfortable financial future or prioritizing time with loved ones, the information presented will help you weigh these considerations effectively. Spots are limited, so don’t miss this opportunity to secure your spot. What You’ll Learn This webinar offers actionable insights into the decision-making process for business owners. Here’s what you can expect to learn: The wide range of reasons why business owners choose to sell, beyond just financial incentives How personal life events, such as family needs and future aspirations, can influence your decision A look at the current M&A market and how buyers are approaching valuations How to balance personal and financial goals using the concept of indifference curves, which help weigh non-monetary values like time with family against financial returns By attending, you’ll gain the tools to make a decision that aligns with your long-term vision—both personally and financially. Spots Are Filling Fast – Register Now! If you’re ready to gain clarity on your motivations for selling and align your decision with both your personal and financial goals, this is the webinar for you. Don’t miss out—register now and take the first step toward making a well-informed, strategic decision about the future of your business. ABOUT BENCHMARK INTERNATIONAL: Benchmark International is a global M&A firm that provides business owners with creative, value-maximizing solutions for growing and exiting their businesses. Benchmark International has handled over $11 billion in transaction value across various industries from offices across the world. With decades of M&A experience, Benchmark International’s transaction teams have assisted business owners with achieving their objectives and ensuring the continued growth of their businesses. The firm has also been named the Investment Banking Firm of the Year by The M&A Advisor and the Global M&A Network as well as the #1 Sell-side Exclusive Privately-held M&A Advisor in the World by Pitchbook and Refinitiv's Global League Tables. Contact Details Brittney Zoeller +1 813-898-2350 zoeller@benchmarkintl.com Company Website https://www.benchmarkintl.com/

September 16, 2024 09:54 AM Eastern Daylight Time

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Flash Transforms Parking at Denver International Airport

Flash

Flash, the leading end-to-end parking technology platform, announced today it has completed an overhaul of public and employee parking at Denver International Airport (DEN) through a contract the City and County of Denver awarded in August 2024. In just 22 days, Flash deployed its platform across the airport’s nine public and employee parking garages and lots, bringing a state-of-the-art parking experience to DEN’s 40,000 employees and the 77.8 million passengers they serve annually. "Flash’s commitment to DEN has been tremendous and we look forward to a bright future that provides innovative solutions to improve the customer experience," said Mark Nagel, Senior Vice President of Parking and Commercial Transportation, Denver International Airport. In its first few weeks of deployment, DEN reports improved traffic flow and reduced wait times for vehicles entering and exiting the airport’s parking facilities. DEN’s deployment of Flash’s platform spans 144 lanes and features 137 kiosks, 97 license plate recognition (LPR) lanes, and 49 automatic vehicle identification (AVI) lanes. With the new AVI lanes, employees can enter and exit automatically in seconds via vehicle-mounted passes that require no interaction with their phones or kiosks. “DEN is the sixth busiest airport in the world and sees millions of parking transactions each year, requiring the highest service level,” said Flash CEO Dan Sharplin. “Our technology breadth and industry-leading scale, plus our maniacal focus on the driver experience, made us confident we could support DEN’s traffic volumes and service levels while getting passengers and employees through parking transactions quickly, and it’s hugely gratifying to see it live.” DEN also benefits from the Flash platform’s design as an enhanced cloud-based parking solution. In the event of an internet, payment processor, network or cloud disruption, the platform maintains continuous operations and critical payment processing capabilities so the airport’s parking facilities stay up and running. About Flash Flash is a pioneering technology company bringing seamless parking and EV charging experiences to drivers through a first-of-its-kind digital ecosystem. Flash’s platform connects reservable parking and charging in the apps drivers use every day with garage, surface lot, event, and valet parking locations—connected and controlled via a cloud-based operating system with unrivaled intelligence. Customer-obsessed brands partner with Flash to deliver digital, easy-to-use, reliable, and increasingly frictionless experiences to drivers eager to pay for a solution that eliminates wasted time, excess emissions, and stress. The solution has arrived.. Visit www.flashparking.com to learn more. Contact Details Ray Young +1 512-694-6097 ray@razorsharppr.com Company Website https://www.flashparking.com/

September 12, 2024 09:00 AM Central Daylight Time

This EV-Based Small Cap Has Partnerships With Walmart, NASA And The U.S. Postal Service – Is It On Your Radar?

Benzinga

By Meg Flippin, Benzinga Canoo Inc. (NASDAQ: GOEV), a high-tech advanced mobility company bringing electric vehicles – namely lifestyle delivery vehicles – to commercial operators, seems to have made strides in its quest to create a state-of-the-art EV commercial fleet. The company has inked deals with some of the biggest names in the U.S., including Walmart Inc. (NYSE: WMT), the U.S. Postal Service, the Department of Defense and even NASA. So what makes these large industry players and government agencies want to partner with a relatively unknown brand? After all, Canoo doesn’t have the name recognition of Tesla Inc. (NASDAQ: TSLA). However, it does have scalable technology, which it says sets it apart. EV Is Here to Stay Over the long haul, electric fleets for commercial and government customers have a lower total cost of ownership and don’t require costly fuel. But Canoo says it takes it a step further by using one-third the parts of traditional internal combustion engines (ICEs). The maintenance schedule is almost an afterthought thanks to its advanced computer architecture, which in most cases, can remotely diagnose and repair its EVs via over-the-air (OTA) software. The company also offers a warranty that covers up to eight years, something not common in the auto industry. Canoo is going after the last-mile delivery market with its fully electric Lifestyle Delivery Vehicles (LDV). The LDVs have a last-mile delivery optimized cabin and customized cargo space. Last-mile delivery refers to the very last step of the delivery process when a parcel is moved from one location to another. Canoo reports that it utilizes true steer-by-wire technology, reducing moving parts and cabin intrusion – resulting in more usable interior space, better driver ergonomics and the addition of a panoramic window to improve road visibility. The LDV is engineered for high-frequency stop-and-go deliveries and speedy vehicle-to-door drop-off, including grocery and food/meal delivery, says Canoo. Walmart Is In All those attributes are part of what led Walmart to select Canoo as its EV fleet provider. Walmart inked a deal to purchase 4,500 all-electric delivery vehicles from Canoo, beginning with the LDV. The retailer has the option to purchase up to 10,000 units. The vehicles are to be used to deliver online orders in a sustainable way which will also contribute to Walmart’s goal to achieve zero emissions by 2040, the companies said when originally announcing the deal. Canoo is headquartered in Justin, TX, and operates manufacturing sites in Oklahoma. While that is Canoo’s biggest order to date, the company is also making inroads with the U.S. government, inking deals with NASA, the Department of Defense and the U.S. Postal Service. All have the potential to expand into something more. Take the U.S. Post Office deal for starters. The postal service agreed to buy six right-hand drive versions of the LDV 190 as part of its move to electrify and modernize the postal service’s delivery fleet. Canoo delivered the vehicles this May, and the USPS is using them on mail routes. Additionally, the USPS is investing $40 billion to upgrade and improve the organization's processing, transportation and delivery networks. If it likes what it sees from Canoo, that could mean more purchases down the road. Meanwhile, NASA had also purchased three Crew Transportation Vehicles (CTVs) to transport the astronauts to the launch pad for the Artemis lunar missions. The CTVs are engineered to carry fully suited astronauts, flight support crew and equipment to the launch pad. “We are thrilled to be a part of the Artemis missions and to deliver NASA’s first zero-emission built for mission crew transportation vehicles,” said Tony Aquila, Chairman and CEO of Canoo. “It’s a very proud day for Canoo and all of our partners who worked so hard to ensure we perform our part to transport the astronauts for the first nine miles of every launch.” Beyond LDVs Beyond electric vehicles, Canoo is busy supplying batteries to the Department of Defense, expanding a deal with the U.S. Navy. Canoo’s proprietary battery system is modular and can support various military applications and configurations. The batteries harbor 5kWh modules that utilize 2170 cylindrical cells, but can fit other form factors and cell chemistries. The company says the expansion of the partnership further validates its technology and reliability. It is also delivering the Light Tactical Vehicle (LTV) to the U.S. Army. From fully electric vehicles that can transport cargo, goods and people to batteries powered by wind and solar, Canoo is doing its part for a greener tomorrow. It may not be a household name yet, but with some big-name players as partners, it's one investors may want to keep an eye on. Keep a look out for more Canoo Inc. announcements here. Featured photo courtesy of Canoo. Benzinga is a leading financial media and data provider, known for delivering accurate, timely, and actionable financial information to empower investors and traders. This post contains sponsored content. This content is for informational purposes only and is not intended to be investing advice. Contact Details Benzinga +1 877-440-9464 info@benzinga.com Company Website http://www.benzinga.com

September 12, 2024 09:00 AM Eastern Daylight Time

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