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Poolbeg Pharma upbeat on preliminary influenza drug results

Poolbeg Pharma PLC

Poolbeg Pharma PLC (OTCQB:POLBF) CEO Jeremy Skillington speaks to Proactive after announcing initial data analysis, including a 'clear dose-related response', for its drug, POLB 001, a potential treatment for severe influenza. Skillington says the 'early data readout' indicates that the challenge trial was successful. Contact Details Proactive UK Ltd +44 20 7989 0813 uk@proactiveinvestors.com

January 09, 2023 09:01 AM Eastern Standard Time

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VinFuture foundation officially calls for nominations for the 2023 season

Vingroup

HANOI, VIETNAM - Media OutReach - 9 January 2023 - The VinFuture Prize officially kicks off its 2023 season with the nomination period open from 14:00 January 9 th, 2023, to 14:00 May 15 th, 2023 (GMT+7). The 3 rd season of the VinFuture Prize is focused on scientific and technological innovations and solutions that help promote resilient and sustainable development amid the forecasted global socioeconomic challenges in 2023. In 2023, humanity will face many challenges due to the impact of global conflicts and economic challenges. According to the World Food Program, an additional 50 million people could be on the brink of starvation by 2023. In addition, global energy consumption is expected to increase amid slow growth and high energy prices. The shortage of gas supply can force countries to continue using fossil fuels, thus slowing down the transition to green energy. With its vision and mission of "science for humanity," the 2023 VinFuture Prize aims to recognize and honor scientific research and technological breakthroughs, thereby contributing to resolving problems that humanity is facing, and facilitating sustainable development for the future. Prof. Sir Richard Henry Friend, Chair of the VinFuture Prize Council, shared: "When we look at the broad fields, it's interesting to see how global sentiment has changed. We're increasingly concerned about global well-being and anxious about a stable and sustainable life after unpredictable incidents. We aim to search for innovations and breakthroughs across all fields to honor scientific innovations that create positive and sustainable changes in the lives of many people. We believe this year's nomination will receive more quality nominations, thus increasing the opportunities to find worthy scientific works and research." To participate in the 2023 VinFuture Prize, scientific and technological innovations and solutions must fully meet the Prize's nomination criteria* and be nominated by prestigious organizations or individuals in the field of science and technology worldwide. Nominated projects will be screened and chosen by the VinFuture Prize's Pre-Screening Committee and Prize Council, composed of leading scientists and experts who have won prestigious awards, such as Nobel, Turing, and Millennium Technology prizes. Previously, the 2022 VinFuture Prize received an exceptional response from the global science and technology community, with 970 quality nominations from scientists, researchers, and inventors from six continents. The 2022 VinFuture Grand Prize (worth US$3 million) was awarded to five scientists: Professor Sir Tim Berners-Lee, Dr. Vinton Cerf, Dr. Emmanuel Desurvire, Dr. Robert Kahn, and Professor Sir David Payne for their ground-breaking research on global network technology. The 2022 VinFuture Special Prize for Outstanding Achievements in Emerging Fields was awarded to Dr. Demis Hassabis and Dr. John Jumper for their pioneering work on AlphaFold 2 - an artificial intelligence program that has revolutionized the modeling of protein structures. The 2022 VinFuture Special Prize for Developing Country Innovators was awarded to Professor Thalappil Pradeep for his development of a low-cost filtration system to remove arsenic and other heavy metals from groundwater. The 2022 VinFuture Special Prize for Female Innovators honored Professor Pamela Ronald for her breakthroughs in isolating the Sub1A gene which facilitated the development of submergence-tolerant rice varieties. The 2023 VinFuture Prize's Nomination Portal is available at: https://online.vinfutureprize.org/nomination For more details about the Prize: * 10 criteria for nomination to the VinFuture Prize: Detailed instructions on the nomination process and form: Frequently asked questions: List of VinFuture Prize Laureates announced at the award ceremony on December 20th, 2022 with information about the awarded innovations: There should be clear evidence, or potential, for an end-product or service based on the solution, which has an everyday practical application; Solutions should have already benefited millions of people in the past 10 years for the Grand Prize, or have the potential to benefit millions of people in the next 10 years for the Special Prizes; Solutions should be aligned with one or more of the United Nation's SDGs; Solutions must be scientifically proven (i.e., there should be clear evidence of passing relevant scientific trials, and in the case of research, it must be empirically proven or widely reviewed); Open to researchers or inventors who were involved in developing the underlying solutions, and not entrepreneurs or corporates who helped in the commercialization/diffusion of the technology; End-products of the research should benefit people globally, including those from developing and less developed countries, as well as lower-income and disadvantaged communities; Open to individuals or teams of researchers/inventors; Preferences are considered for nominees in the active stages of their careers; Same individual/team can be nominated for one or more of the VinFuture Special Prizes if eligible; Research/Solution/Invention can be underpinned in any discipline of science, engineering, or technology, including potentially multi-disciplinary approaches. About VinFuture Foundation The VinFuture Foundation, established on December 20th, 2020 on the occasion of International Human Solidarity Day, is a non-profit organization co-founded by billionaire Pham Nhat Vuong and his wife, Mrs. Pham Thu Huong. The Foundation's vision is catalyzing meaningful change in the everyday lives of millions of people by honoring transformational technological innovations at a global scale. The Foundation's core activity is awarding the annual VinFuture Prize for breakthrough scientific and technological innovations that have created or have the potential to create meaningful changes in the everyday lives of millions of people across the planet. The VinFuture Prize consists of four prize categories, of which the Grand Prize – with a value of US$3 million – is one of the largest annual global prizes, and three Special Prizes, worth US$500,000 each, are dedicated to Female Innovators, Innovators from Developing Countries, and Innovators with Outstanding Achievements in Emerging Fields. In addition, the Foundation conducts many activities to accomplish its mission, such as funding academic activities, catalyzing intellectual connections, collaborating in sci-tech development, and promoting STEM education. Contact Details Media Contact v.chidqd1@vingroup.net Company Website https://online.vinfutureprize.org/nomination

January 09, 2023 08:30 AM Eastern Standard Time

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Kadimastem Announces it raised appx 7.5 million NIS by rights offering

Kadimastem2

Kadimastem Ltd. (TASE: KDST), a clinical stage cell therapy company developing treatments for ALS and diabetes, announces the raising of 7.5 million NIS in a rights offering. The company's main stakeholders, Prof. Michel Revel and Mr. Julian Ruggeri, and the European Alpha Capital Anstalt, expressed confidence in the company and participated in the rights offering. Cybele Investments served as a distributor to the transaction. Attorneys Reut Alfiah and Oded Har-Even, of Sullivan & Worcester, accompanied the company in the transaction. A little over a week ago, the company announced the approval of a NIS 3.5 million (US$1 million) budget grant by Israel-U.S. Binational Industrial R&D Foundation (BIRD) to support Kadimastem and iTolerance Inc.’s joint project to develop and commercialize a breakthrough regenerative technology to cure diabetes without the need for chronic immuno-suppression. The total project budget is NIS 7 million, for a period of 30 months. iTolerance is a US company based in Florida that has developed an innovative technology (iTol 100) with the aim of enabling the transplantation of allogenic cells (genetically different from the patient) without tissue matching and without suppressing the recipient's immune system. In preparation for the rights offering, the Company provided a voluntary update on its activities. Regarding the AstroRX product for the treatment of ALS, the company has updated that it intends to submit an IND to the FDA for a phase II/a clinical trial by the end of January 2023. For the submission, the company hired an American CRO for the purpose of planning and implementing the clinical trial. In addition, the company is in contact with experts in the field in the U.S., in preparation for their potential participation in the execution of the clinical trial and is examining potential sites for execution of the experiment. Regarding the IsletRX product for the treatment of diabetes, the company has updated that following the engagement with the French company Defymed, which develops advanced encapsulation solutions for examining an integrated solution for the treatment of diabetics, the companies are in advanced negotiations for cooperation to develop a joint product in the field of diabetes. Regarding the intention to list on NASDAQ, the company has updated that it is in the process of preparing for a dual listing on NASDAQ. The Company also updated that it is in initial communication with a private company to examine a strategic investment in the company and/or strategic cooperation. Asaf Shiloni, CEO: "The raise from the main stakeholders who have been accompanying the company since its inception, gives a boost to the company's development plan and will allow us to securely move forward with the submission of the IND to the American’s FDA, and to move towards a phase IIa clinical trial in the US for patients with ALS." Ronen Twito, Chairman: "We welcome the confidence of the company's main stakeholders in its management, the company's assets, and the quality of science, at a time when the world's capital markets are unstable. I am confident that we will continue to lead Kadimastem to successes and the realization of its potential." About Kadimastem Kadimastem is a clinical stage cell therapy company, developing and manufacturing "off-the-shelf", allogeneic, proprietary cell products based on its technology platform for the expansion and differentiation of Human Embryonic Stem Cells (hESCs) into functional cells. AstroRx®, the company's lead product, is an astrocyte cell therapy in clinical development for the treatment for ALS and in pre-clinical studies for other neurodegenerative indications. IsletRx is the company's treatment for diabetes. IsletRx is comprised of functional, insulin and glucagon producing and releasing pancreatic islet cells, intended to treat and potentially cure patients with insulin-dependent diabetes. Kadimastem was founded by Professor Michel Revel, CSO of the company and Professor Emeritus of Molecular Genetics at the Weizmann Institute of Science. Professor Revel received the Israel Prize for the invention and development of Rebif®, a multiple sclerosis blockbuster drug sold worldwide. Kadimastem is traded on the Tel Aviv Stock Exchange (TASE: KDST). Contact Details Kadimastem Sarah Bazak s.bazak@kadimastem.com Lior lior@gotlive-ir.co.il, s.bazak@kadimastem.com

January 09, 2023 07:01 AM Eastern Standard Time

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Over 60% Of Americans Will Experience Back Pain At Some Point - FloSpine’s Solution Makes Surgery Easier, Cheaper, And More Accessible

FloSpine

By Faith Ashmore, Benzinga Interested in investing in FloSpine’s campaign? Click here to get started! Outpatient and inpatient are entirely different worlds in healthcare. Inpatient care refers to anything that happens in a hospital setting and is designed to provide care for patients who might require overnight care. On the other hand, outpatient facilities are built to accommodate procedures that can be done within a day and require less monitoring afterward. Outpatient care, where applicable, has lots of benefits for the patient and practitioners alike. Outpatient care is typically much cheaper than inpatient; there are no hidden or additional fees for things like maintaining a large staff and resources. Sometimes it costs thousands of dollars more for inpatient care versus outpatient. Patients are also able to recover in the comfort of their own homes with outpatient care, a huge draw to many people. COVID-19 has shined a spotlight on the benefits of outpatient facilities, sometimes known as ambulatory surgery centers (ASCs). High patient volumes at hospitals left providers itching for more facilities to provide patients with care at. Not to mention ambulatory surgery centers have resulted in millions of dollars of healthcare savings for providers. Ambulatory surgery centers are only expected to grow in the coming years. The market is expected to grow steadily at a CAGR of 7.5% through 2029. As the Centers for Medicare & Medicaid Services announce more procedures that are approved for outpatient facilities, the popularity of ambulatory surgery centers will only grow further. Spinal Surgery Is Moving To ASCs While major spinal surgery will remain in the jurisdiction of major hospitals, smaller surgeries or minimally invasive spinal procedures are having success at ASCs. Currently, there are more than 160 outpatient surgery facilities in the U.S. that specialize in spinal care. According to data compiled by CardinalHealth, the spine ASC market is expected to grow 200% in the coming years. Spinal fusion implants are one of the approved procedures that are having success in ASCs. Spinal stenosis occurs when a patient’s spinal disc begins to collapse and pinch the nerve roots and spinal cord; this breakdown of the spinal cord can cause pain, mobility issues, and overall deterioration of health. Traditionally practitioners have implanted rods and screws to correct spinal stenosis. FloSpine has pioneered a new device that can replace the existing rod and screw fusion solution. Their proprietary product, The KeyLift™ Device, is inserted through a small incision (about 2 inches). This device and procedure lead to faster patient recovery and less blood loss while limiting the chance of bone cracking because of how it fits in between the laminar of the spine. The company has already had success in the minimally invasive surgical technique industry with its Largo®, Canaveral®, and Panama® products. It is currently hosting a raise to finish the development and execution of its KeyLift Device. One major benefit of the KeyLift Device is the procedure can be performed in ASCs and limits costs to the patient while increasing long-term spinal health. Approximately 60-70% of Americans will experience back pain at some point in their life, making the importance of innovative spinal fusion implants incredibly important. FloSpine could be a leading innovator in the space helping make the lives of many easier. This article was originally published on Benzinga here. At FloSpine, we have developed a new solution to treat back pain, the KeyLift™. The KeyLift™ is implanted and expands to release nerves that are under pressure due to aging or injury. This condition is known as lumbar spinal stenosis and we believe that we have a new solution to treat it. We consider ourselves to be a leading medical device company applying new technology and design concepts to solve medical problems for the human spinal column. With 6 US patents, and 4 Patent Applications (2 International), we are in review with the FDA for the latest solution for back pain: KeyLift™. FloSpine® is registered as a Medical Device Manufacturer with the Food and Drug Administration (FDA). This post contains sponsored advertising content. This content is for informational purposes only and not intended to be investing advice. Contact Details Waldi Harris wharris@flospine.com

January 06, 2023 08:05 AM Eastern Standard Time

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Oxford Cannabinoid Technologies "ready to go" after phase 1 trial submission

Oxford Cannabinoid Technologies Holdings PLC

Contact Details Proactive UK Ltd +44 20 7989 0813 uk@proactiveinvestors.com

January 06, 2023 04:58 AM Eastern Standard Time

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Change Addressing Disparity for Black Kidney Patients Takes Effect

United Network for Organ Sharing

Black patients disadvantaged by a race-based measure of kidney health will now be eligible to receive modifications to their waiting time, potentially improving their prioritization for transplant, according to a new policy passed by the Organ Procurement and Transplantation Network (OPTN) Board. United Network for Organ Sharing (UNOS), the organization that powers the nation’s donation and transplant system, serves as the OPTN under federal contract. The new policy went into effect today, January 5, 2023. The change was unanimously approved by the OPTN Board on December 5, 2022. The policy is intended to address disparities in waiting times faced by Black patients on the kidney transplant waitlist. Some of these patients were disadvantaged by the earlier use of a measure that took race into account when measuring kidney function. For years, some calculations (known as eGFR) included a modifier for Black patients based on outdated assumptions about race and biology. This practice led to the severity of kidney disease in Black patients being systemically underestimated. It may have also negatively affected when Black patients got added to the national waitlist. In June 2022, the OPTN Board approved a policy that required transplant hospitals no longer use race-based calculations when estimating a patient’s kidney health. “This action underscores our commitment to equity in access to transplantation for all candidates,” said Jerry McCauley, M.D., M.P.H., president of the board. “We and many other organizations have now prohibited the use of a race-based calculation that has unfairly delayed care for many Black patients with kidney failure. Waiting time for a transplant is a major factor in the priority that kidney candidates receive. Thus, we are acting along with kidney transplant programs nationwide to ensure that any candidates known to have been disadvantaged by a race-inclusive GFR calculation will receive all the waiting time credit for which they qualify, as soon as possible.” “So many African-Americans have been affected by the use of race-inclusive calculations, and have become very ill or have died waiting for the opportunity to list for a kidney transplant,” said Precious McCowan, a kidney recipient and donor mother who serves on the OPTN Kidney Transplantation Committee, which developed and co-sponsored the policy with the OPTN Minority Affairs Committee. “With the new policy change, I envision more African-Americans having an equal opportunity to list for kidney transplantation.” Transplant programs must comply with the policy by January 3, 2024, which will include reviewing their lists of waitlisted candidates to identify those who may have been impacted by the use of the race-based calculation. About UNOS United Network for Organ Sharing (UNOS) is a non-profit, charitable organization that serves as the Organ Procurement and Transplantation Network (OPTN) under contract with the federal government. The OPTN helps create and define organ allocation and distribution policies that make the best use of donated organs. This process involves continuously evaluating new advances and discoveries so policies can be adapted to best serve patients waiting for transplants. All transplant programs and organ procurement organizations throughout the country are OPTN members and are obligated to follow the policies the OPTN creates for allocating organs. Contact Details United Network for Organ Sharing Anne Paschke +1 804-782-4730 anne.paschke@unos.org Company Website https://unos.org

January 05, 2023 02:39 PM Eastern Standard Time

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NuggMD releases landmark 210k-record patient study on medical cannabis trends

NuggMD

As legal cannabis continues to enjoy broad, bipartisan support among the general public and as more states legalize the substance for either medical or recreational purposes, a recently released landmark study sheds new light on the conditions for which patients seek medical cannabis and how those conditions vary by geographic region, age, and gender identity. The study, the 2022 Cannabis Conditions Report, was conducted by NuggMD using more than 210,000 anonymized patient records, among the largest data sets of its kind. NuggMD is a telemedicine provider that helps patients obtain medical cannabis cards in 22 states. It conducted the study in order to add more facts to the prevailing dialogue about the addition of medical cannabis to a treatment regimen. The full report is available here. It was first reported by Marijuana Moment, one of the nation’s leading trackers of developments and news in the cannabis industry. Concurrent with its Conditions Report, NuggMD also released the details of a complementary survey of more than 500 current medical cannabis card-holders. Importantly, 68 percent of respondents said they have ceased or reduced other pharmaceutical treatments since incorporating medical cannabis. More than 80 percent of respondents said they are comfortable discussing medical cannabis with their doctors, and more than 94 percent said cannabis provides to them moderate or total relief of the conditions for which they sought treatment. "The evidence here is clear: medical cannabis works. It provides relief for a wide variety of conditions. More importantly, it's giving patients an alternative to dangerously addictive, often deadly pharmaceuticals. More than a century of disinformation and propaganda peddled by cannabis foes does not change these facts,” said Alex Milligan, co-founder and chief marketing officer of NuggMD. Analysis: Inconsistent standards limit access and create unreliable data Still, a significant barrier to access is how states limit the qualifying conditions for which a patient may be recommended medical cannabis. In some states, legislators have expanded their regulations to include more qualifying conditions or to allow physicians to recommend medical cannabis in broad terms, such as for treatment of a “debilitating medical condition.” Other states continue to unjustly prohibit their residents from accessing this form of healthcare. Of note, the states that allow physicians to determine the qualifying condition saw a higher rate of patients reporting “other condition” as a reason they were seeking medical cannabis. Based on that datapoint, NuggMD believes that states with fewer qualifying conditions are either deterring patients from seeking the medication they need or reducing the accuracy of available data by forcing patients in need of medical cannabis to select a comorbidity rather than the primary ailment for which they were seeking an evaluation. A majority of patients in the study listed multiple conditions, which can be expected as many conditions exist co-morbidly. “From a policy standpoint, one piece of low-hanging fruit for lawmakers is more consistency to the qualifying conditions under which states approve medical cannabis licenses for patients,” said Milligan. “The current status quo does not promote equal access to care or the evidence-based evaluation of medical outcomes, which are both cornerstones of other areas of healthcare.” The report was authored by NuggMD's Alexandra Arnett, a University of Maryland School of Pharmacy candidate for a Master of Science in Medical Cannabis Science and Therapeutics. Medical review was provided by Dr. Brian Kessler, MD, Pain Management & Sports Medicine, with analysis, editing, and fact-checking conducted by NuggMD's Tyler Elson and Deb Tharp. About NuggMD NuggMD is the nation's leading medical marijuana technology platform, serving patients in California, Connecticut, Georgia, Illinois, Iowa, Maine, Maryland, Massachusetts, Michigan, Minnesota, Missouri, Montana, Nevada, New Jersey, New York, Ohio, Oklahoma, Pennsylvania, Texas, Vermont, Virginia, and West Virginia. They've connected over 1,000,000 patients face-to-face with their new medical marijuana doctors via their state-of-the-art telemedicine platform. They believe every human being has the right to explore the benefits of medical cannabis and are fully committed to helping each patient explore every option in their journey to wellness. For further information, visit NuggMD.com. Contact Details Andrew Graham andrew.g@getnugg.com Company Website http://www.nuggmd.com

January 05, 2023 02:11 PM Eastern Standard Time

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Variational AI Files Two US Provisional Patents for Potential COVID-19 Drug Created by Generative AI

Variational AI

Variational AI, developer of the Enki™ generative artificial intelligence (AI) drug discovery platform to redefine the economics of drug development, today announced that the company has filed two provisional patents with the United States Patent and Trademark Office (USPTO) related to new chemical entities (NCE) successfully created using generative AI. Variational AI’s protease inhibitors are among the first NCEs created via a purely generative model and will be useful in the development of COVID-19 drugs as part of the company’s coronavirus antiviral program. Of even greater significance, this method underscores the potential of generative AI to create novel, efficacious, safe, and synthesizable molecules. “The filing of these patents is a concrete milestone not just for Variational AI, but for the applicability of generative AI to the domain of drug discovery,” said Handol Kim, co-founder and CEO, Variational AI. “Whereas adoption of AI for drug discovery is accelerating, until now it has been based on older discriminative models. Though powerful, these models are essentially just performing faster and better virtual screening of known or existing molecules. Enki™ does not screen, but rather truly creates new molecules, similar to how other generative AI models like DALL-E and ChatGPT create novel images and text based on prompts. In our case, we use the language of chemistry as prompts to describe the molecules we want.” While generative AI has recently been applied at scale to the creation of novel images, text, music, video, and software code, the successful application of generative AI to drug discovery is still nascent but potentially transformative. Variational AI’s platform created two novel lead candidates that each bind differently and distinctly to the SARS-CoV-2 main protease, the most promising therapeutic target implicated with COVID-19 across variants and potentially other coronaviruses. The platform is based on a generative model framework known as a variational autoencoder (VAE) and created these lead candidates after being trained on large sets of public and proprietary data including older SARS-CoV (SARS) main protease data. The candidates demonstrated potency, selectivity, and novel binding modes on the SARS-CoV-2 main protease that show potentially better safety profiles compared to the existing standard of care. Variational AI is now focused on training Enki™ for multiple drug targets in oncology and making rapid progress in this disease area, leveraging learnings from its success in antivirals, as well as other disease areas. “Our team of machine learning researchers has been developing and applying generative models for years, long before the recent interest,” said Jason Rolfe, co-founder and CTO, Variational AI. “Drug discovery is a massively difficult undertaking, yet we continue to make rapid progress working hand-in-hand with our drug discovery team as we move to addressing unmet medical needs in oncology and beyond.” Funding for this work was supported in part by Canada’s Digital Technology Supercluster in collaboration with adMare BioInnovations and the University of British Columbia. About Variational AI Variational AI uses generative AI to create novel and diverse compounds that are optimized for multiple properties to avoid the most common causes of drug attrition and increase clinical probability of success. Variational AI works with leading biopharmaceutical partners and is developing its own internal pipeline. To learn more, visit https://variational.ai. Contact Details SVM Public Relations Jordan Bouclin +1 401-490-9700 variationalai@svmpr.com Company Website https://variational.ai/

January 05, 2023 10:00 AM Eastern Standard Time

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10 Best Essay Writing Services in the USA: TOP College Paper Writing Websites

Genuine Papers

A stitch in time saves nine. So, as a student, you may want to ask, “Can I prevent low grades in my academic essays?” The answer is yes, especially with the assistance of paper writing services waiting for you to take advantage of their experienced writers. But are you ready to meet them? Before sharing this list of the TOP rated essay writing companies in the United States, you should know the criteria for choosing these websites. To start with, they have excellent writing consistency with many repeat customers. Furthermore, first-time buyers often commend them for quality and prompt delivery. These services have respect for deadlines and submission dates, making them the joy of many students worldwide. Again, these are the best American essay writing services available online today, because of their excellent customer support. Their customer care team is fully armed with all it takes to answer all your inquiries and tend to questions posed to them when you reach out. Also, they keep tabs on your order on their platform. If you are looking for more reasons to check them out, know that when you hire them, you will receive plagiarism-free content. That is, your essay is original. Thus, you would not have to worry about it being flagged by your professor or any plagiarism checker software. All you have to do is check the internet for more proof of excellence. The digital world is littered with many positive reviews. So, do you want to be one of their lucky customers? To make things much easier for you, we have provided a well-curated list of the best essay writing services in the next college season in the United States. These companies were well researched and added to this updated in January, 2023 rating based on excellent turn-ins over the years from their clients and prompt delivery. The List of the 10 Best Essay Writing Services in USA PaperHelp - the best college essay writing service today in the United States. 99Papers - recommended for New York students. SpeedyPaper - same-day writing company. EssayPro - the cheapest U.S. paper writing provider in 2023. MyAdmissionEssay - the best essay service in Florida. EssayBox - a professional American website to hire writers online. IQEssay - "do my essay" qualified writers from Ohio. Studdit - newest company to buy an essay from Texas. SuperbPaper - company from Arizona that can write your essay. PaperCoach - trusted MBA essay writing service est. 2012. Now, we can see what advantages they have and what features they may cover for students looking to get the best service for their grade. Let's check full trusted reviews from experts for each website. 1. PaperHelp PaperHelp is one of the most popular essay writing services in the United States today. And their place in the market is that of the top seat in 2023. Well, they go to that level from sheer grit in their excellence creed since their inception in 2008. And that is reflected in the quality of their deliveries to their customers. When you order from them, they strive to give an experience commensurate with their creed of being the best essay writing service. The reason for that is not far-fetched. They simply realize that human referrals are the best way to keep their business booming. So, if they make you feel good, they have invested in their publicity among your friends and colleagues in school. Ordinarily, you are bound to get hooked on their website. Most customers buy from them because of how super intuitive their interface is. It is both easy to understand and navigate. The website layout, design, graphics, and interactions are cool, making you stay on the website long enough to order from them. All these contribute to their efforts to give you the best experience possible as you order. Thus, they do not only deliver excellent written-from-the-scratch content for you, but they also make sure that your process of ordering and getting the content delivered to you is as seamless as possible. Their customer journey reflects how much they put into your work to make t come out beautifully. Now, nice graphics aside, can they write your essays well? With tons of feedback, reviews, and comments from many reliable sources, PaperHelp does not only have first-time buyers. They have a ton of repeat buyers who are always on edge to order from them. Why? Because the platform delivers excellent delivery to them all the time. So, why go elsewhere when I am being served excellently here? Right? Thus, you should know that PaperHelp creates fresh content for your essays and promptly delivers with 0% plagiarism. And they can also tend to all forms of essay writing services you might require. That is, from a highschooler essay to the most academically complex ones such as Ph.D. dissertations. All are welcome and can be excellently written by their professional writers. Speaking of professional writers, they have an army of seasoned writing specialists with rich academic writing experience. Most of these writers are academics themselves. So, they are familiar with the in and out of the most complex essays, theses, and dissertations. On the PaperHelp platform, these writers can turn in essays with an urgent deadline as fast as 3 hours. And with just $10.00, you can have a good paper written for you. Also, you can monitor the progress of your work on the control panel with options for other means of communication, such as toll-free numbers, Skype, Facebook Messenger, and the PaperHelp app. 2. 99Papers Are you a New York student? Then get in here. 99Papers is perhaps the best writing service you will encounter as a student. As one of the oldest platforms, they have rich experience in how to write essays for varying academic difficulties. All you have to do is order from them and see the magic. You may be wondering what is unique about them. Of course, their existence is a distinctive factor. However, it is not the major propelling reason many people buy from them. They simply deliver quality. This feature stands out to most of their customers. They create original essays, not plagiarized ones. They offer plagiarism reports on request. Further, they have a considerably low-price range for an essay per page. By the way, they are one of the essay writing services with a wide range of essays they can write. Whether you are a high schooler looking to work on a mini-essay or a full-blown academic looking to get an A in your dissertation as a Master's student, all of your writing needs can be well met at 99Papers. And with just $9,95 per page, you get access to a well-written essay. This is coupled with several discounts on their website that you can benefit from when ordering, especially if it is your first order. You also enjoy some premium features with this piece, such as proofreading or plagiarism check. Unlimited revisions, bibliography, and title pages are also free of charge on their platform. Little wonder many students looking for where to save some buck and still get stellar work opt for this writing service. Also, 99Papers places a premium on their writers. They are quite strict on the admission of people into their writing intelligentsia. They verify their writers' academic backgrounds and only hire those with rich writing and knowledge experience. Interestingly, some writing experts work in reputable universities such as Yale, Cambridge, Oxford, Berkeley, etc. All these extra efforts in recruitment are so that they can always serve the customers with only quality orders. Similarly, their customer support is also made of quick-response and prompt personnel. Do you know that their average response time is 10 seconds? Yes, that is quite remarkable for a company as big as that. 3. SpeedyPaper This essay writing service is called SpeedyPaper for a reason! Their response rate to essay delivery is one of the fastest in the entire American market. And it is one of their major selling points. Most of their buyers, mostly from California, reach out to them when they need an essay written within hours. And when you make this kind of quick order, their prices do not unnecessarily shoot off the roof to scare you away. No. Another thing that stands out for most people is the level of quality retention. That is, their essays are both quickly done and excellently written. With them, you can expect your essay to be well-researched and grammatically compliant without plagiarizing or stealing from another source. If you need an essay in 6 hours, they can take on the order and deliver it efficiently. Further, if you are looking for a synonym for SpeedyPaper's support team, the phrase you are looking for might be "as fast as lightning". They respond swiftly to all new buyers' inquiries, complaints, and comments from their current customers. Little wonder they have an outstanding reputation in public for their beautiful work culture and customer relations. They also have a high rating with many review sites that have taken a recount of how good their service is. The customer support swiftness is part of the SpeedyPaper attempt to make your order from them and enjoy one of the best customer services out there in the essay writing services space. In addition, their pricing is quite affordable for most people. Their rates start at $9 per page for high-school-level writing on a 14-day deadline. However, several things may affect the price by lowering or increasing it. And one of these is the use of coupons on their websites. That might lower how much you have to pay cumulatively for your order. If you request a plagiarism report or the deadline for your turn-in is shorter than usual, you might have to pay more than what you would ordinarily have to pay. 4. EssayPro If you mention the names of the best cheap essay writing services from U.S., EssayPro will make its way to that updated list. The reason for this high ranking is not far-fetched; they have etched a distinct experience in the minds of all their customers. And that is the fact that they offer a wide range of services on their platform. With all the different forms of essays you can get with them, you can also rest assured that your orders are safe and will be done to your taste. They do essay writing, editing, rewriting, as well as proofreading. Many buyers have found themselves iterating between EssayPro and other writing services, yet choosing the former every time they are left to pick where to get their essays done. This shows that this writing service is trusted by many in the market. Checking out their website gives you a lot of straightforward ease with ordering. For example, the first thing you see on their website is a price calculator. It asks for your preferences, such as the paper's type, length, and deadline. This is to determine a minimum price per page. You can get a well-written essay for just $10.8 per page. And that is especially if the deadline is around 5 days. However, depending on the academic difficulty and the short deadline involved in the order, the price might go up to around $14.36 per page. And the price is quite reasonable compared to many other services in the market. Further, EssayPro also runs discounts that many of its buyers look forward to. Usually, the discounts depend on the number of pages you are ordering and the times you have ordered from them. The discounts range between 10% to 33%. Also, their FAQ section reveals that there is a referral program. And you get a $10 PayPal transfer when you bring a new customer, and they order from their platform. 5. MyAdmissionEssay Are you in Florida and looking for the “write my essay service” you should patronize? Then your search has ended. EssayFactory has proven itself as a strong name for delivering excellent content for its customers. They are known for creating from-the-scratch content with no plagiarism. They are so confident in their essays that they are willing to provide plagiarism checks for all that request them. As a result, many students have made them solace when it comes to writing excellent essays to achieve better academic results. Be it a high school grade essay or more academically difficult ones such as theses or dissertations; they are ready to woe your teachers and supervisors with their excellent writing skills. Furthermore, they have such a good reputation for their writing in the USA because of their team of expert writers. These folks strive to achieve top-grade writing every time they touch the keyboard. Every time they write, their works go through a thorough and immersive plagiarism check and review before such a paper is delivered. As a result, they ensure minimal to zero grammar or spelling mistakes. Not only that, but they also ensure that you receive prompt delivery of your order. Interestingly, they have one of the best support teams in the industry. Their customer support teams are available 24/7, and they are ready to attend to all your inquiries and complaints if you ever have any. They are also known for fast response and finding the best solutions that suit you as an individual and not generic responses that would put you off balance. They are available to speak to you via chat or phone. You can also access them via the email indicated on the website. 6. EssayBox EssayBox is another notable name in the U.S. essay writing service market. From ordering on their website to receiving your order, this writing service strives to give you a seamless experience with getting your essay written on their platform. Whether it is a basic high school essay or a full-blown dissertation or thesis, you can rest assured that you will be getting good and original content at the end of the delivery. Ordering on their website is quite easy. And this is because their website is suited to give you a great welcoming experience. And it is designed so that all the necessary infographics, promos, discount codes, reviews, and price calculators are available at first contact. Also, the color scheme is carefully chosen. It does not disturb or distract the eyes from the most important details needed. You can put your heart at rest when it comes to the quality of writers on their platform. This is because they hire native speakers who can write effectively in UK English and the US. Their writing specialists undergo some language tests before allowing them to take orders on the platform. Thus, as a customer, you can choose the writer you would like to attend to your order based on their qualifications, field of expertise, and experience. In case you are wondering, EssayBox charges $12 per page. However, depending on the specifications of your order, there might be a few tweaks to the eventual price. These specific adds could be the academic difficulty of the paper, deadlines, the number of pages, topics, etc. In addition, they offer services like revisions, inquiry, titles, outlines, and bibliography for free. 7. IQEssay IQEssay is that one-stop shop for all of your essay writing needs. You need not stress too much about most of their papers. Their customers trust them to deliver quality all the time. This is attested to by innumerable comments, reviews, and positive feedback they have garnered over the years of working as a top-notch essay writing company based in Ohio, USA. They are another writing service that most USA students rush to when they need their assignments done. This is because they not only have a sterling reputation for excellent papers written for you, but also deliver your papers promptly. Thus, if you are looking for expert writers from the U.S. who can give you a great paper within a short time frame of delivery, you can check out IQEssay. Since 2005, they have specialized in making geniuses of many students by assisting with papers ranging from short essays to exam notes, proofreading, and editing, or a full dissertation. They also offer some services not common to most essay writings service. And one of them is a CV writing service. They also write personal statements, assignments, etc. In short, they are available to help you to achieve your academic, business, or even personal goals. And with all these, you can be at rest of a high standard work to be done on your work. Not only that, but they also respond promptly to all of your orders regarding delivery. The pricing of IQEssay, like every other platform in the market, can be influenced by the order's specifications. You can get an excellent article within a 30-hour delivery for $30 per page. And this price is influenced by the caliber of writers that work on your order. Also, they give their customers discounts that aid their pay on the platform. A good example is the 20% slash on orders if you are buying paper from them for the first time. 8. Studdit With hundreds of positive reviews about them from Texas college students, Studdit has a strong root in the industry as one of the strongest names. This reputation is one of reliability and trust. They will write your essay and other related writing services like a CV from you from scratch. Not only that, but you would also be able to present a plagiarism-free essay to your supervisor for your dissertation and theses. Little wonder many students keep going back to them to write their academic essays, difficulty level notwithstanding. Thus, whether you are a high schooler needing an assignment written or a postgraduate student looking to wow your supervisor, all writing needs are ably met on the Studdit platform. Further, Studdit can brag of sterling, original, and quick content because of their team of writing specialists. This platform particularly has a great knack for treating its writers well. This unique in-house culture culminates in palpable enthusiasm with their writers to deliver promptly on the tasks assigned to them. As a writer with them, you will not be given a new task unless you have completed the one on your hands. Also, writers are rewarded for bringing clients to Studdit. So, there is enough motivation to round. Thus, you can be assured that, as a client, your essay is being handled by someone happy to do their job. Also, note that Studdit is one of the cheap essay writing services in the market. With just $10, you can get a great paper delivered to you. Also, you could experience the prices jerking up or remaining normal depending on your academic level. However, this does not in any way tamper with the quality of your paper. 9. SuperbPaper SuperbPaper is an Arizona essay writing company that priorities excellence in writing, delivery and discounts. They are also known as the first-class, affordable essay writing service. And this is because they deliver premium quality papers from professional writers and editors. These expert writers that work on their platform create stellar and original content for each student who orders essays on their platform. Also, they deliver their essays speedily. Thus, they respect deadlines and communicate effectively with you. Further, irrespective of your academic level as a student, SuperbPaper is that one-stop shop writing service ready to take on any form of paper. That is, term papers, dissertations, theses, research papers, high school essays, etc., are all what they excellently write on a day-to-day basis. And you can enjoy their services on these essays from $9 per page, depending on their difficulty level. Many customers go back to SuperbPaper because of the laudable work that their customer support team does. They respond to inquiries and complaints quickly. Also, they are available for you throughout the day. 10. PaperCoach PaperCoach is a U.S. writing service that attends to your writing needs. Once you have supplied your order specifications on their website, you are good to go on your order. The writer begins to work on it immediately. Little wonder any student entrusts their MBA essays in the hands of this company. PaperCoach will write you original content from scratch. Also, their content is entirely plagiarism free. Thus, you do not have to be afraid of plagiarism checkers flagging your MBA essays or your supervisor thinking you are fraudulent in any way. PaperCoach has enjoyed a lot of great reviews in the market over the years. And rightly so! The reason for this positive feedback is not far-fetched. The most notable point in most comments is how they quickly turn in client orders. Thus, if you are a student pressed for time, make sure you reach out to PaperCoach, as they are one of the best MBA essay writing services in the industry that prioritize prompt delivery of essays. The writers who work on these original and prompt contents are in categories. You have an opportunity to pick the ones you prefer to work on your order, only that it might increase your price a little. This service also has a strong support team always available to you. They are ready to answer all your questions, including pricing. So you can rest assured that you will get a special delivery at $8 per page. FAQ How an essay writing services work? American essay writing services are one of the easy-to-navigate services in the world presently. And you do not need to search all over the internet to find them. We have carefully curated them for you above. So, as highlighted above, you can choose any of the best essay writing services in 2023. But note that ordering most of these writing services is quick to understand. You do not have to struggle much with them. Most of what you need to make a successful order is on their website. Most of these writing services have great website interfaces. And on these sites, you would be met with a price calculator. This is where you customize your order by adding the essay specifications. That is, you would input the deadline, number of pages, topic of the essay, etc., in the form that doubles as a price calculator. Thus, your essays would be automatically calculated, and you make payments via any channels shown on the site. Then you are good to do! Also, if you have any questions, you can contact customer support on any of these platforms. They are available 24/7 and ready to resolve all your complaints. How much does it cost to order a college paper? The price for ordering a college paper varies. The essay writing service that you choose determines what fee you have to pay. For 99Papers, you enjoy their services and excellent essay delivery for just $9,95 per page. And for PaperHelp, you can buy an essay for $10 per page. These are the base process for these essay writing services. Thus, depending on a couple of factors, your eventual price to be paid might increase cumulatively than what could pass for the normal gross price fee. Some of these additions that jerk up the essay price include the date or time of the deadline. You might have to pay more for the different deadlines if it is much shorter than the stipulated time. The academic level also determines the price. Most of the base prices on the websites are for high school and college undergraduates. For dissertation students, the price might increase. Other factors include special services such as plagiarism reports, the type of writer working on your order, etc. Some platforms also offer discount coupons, so you can leverage that for your fee. Are using an essay writing services in the USA ethical? Yes, there is nothing wrong with using essay writing services. It is legal and ethical to use the help of expert writers to assist in your essays when you cannot work on them yourself. This eases the burden on you and allows you to focus on most things you need. Most of the essays are written from your order specifications. Thus, you are guiding the mind of the writer to help you write based on the resources you have made available. Students who are the breadwinners of their families or those who work two jobs to support themselves through school are incapable of writing essays. There are even students without a proper grasp of the English language. How can they write essays and score high grades in their academic pursuit? Asking for help is not a bad thing and would not be one. Using the services of an essay writing service is simply asking for help from an expert writer. And that's okay and cool. Legitimacy of buying an essays in the United States Buying essays in USA online is 100% legit. However, it depends on where you decide to buy your essays. If you decide to buy them from unverified sites or platforms, you are left alone to face the brunt of whatever comes your way. But to avoid this, we have listed and carefully explored each service we consider the best in the market. And they are all completely legitimate. No need to fear using them. Just get your purse ready and order away! Most of them have a lot of online reviews, so you can check them out before putting your money on any of them to make an essay purchase from any of their writers. Further, you would get fully original content from these websites. Not plagiarized ones that unverified sites bring your way. So, you do not need to be afraid that plagiarism checker software will flag your content or that your supervisor will think you stole the research from somewhere. You would enjoy complete transparency with excellent content delivery. That sound like a legit platform to us. Don't you think? In the same vein, all the credentials that you submit on the website are treated as anonymous and confidential. So they cannot be shared anywhere online. What is the best essay writing service in the USA? PaperHelp is a top-rated American essay writing provider in 2023. They are rated this high because, with them, you enjoy a maximum pricing advantage compared to most platforms in the market. For only $10, all your writing needs can be met per page. And you would be taken aback at the level of excellence that has gone into the production of each original content of your essay. At the same time, the work would be delivered swiftly without tampering with the quality of the content. You can enjoy all these freebies and more with revisions on the PaperHelp platform. And in case you have any inquiries, you can easily contact their customer support team, who are always hands-ready to pick up your call or chat with you via any of their social media handles, especially Facebook Messenger. You can also choose to speak with them via phone if you so choose. How to hire somebody, who can write a professional essay for me? There are tons of ways to hire somebody to write essays for you. However, many of these paths lead to meeting the wrong folks on the internet. Fraudsters posing as good essay writing services are very rampant these days. And the only way to interact with trusted and reliable professional services online is via the lists of services we have made available above. These have a simple approach to ordering from them. And they are always ready to be hired to work on any of your writing needs that might surface at any time. Hire somebody to write your essays for you is easy today in USA. Since you have the internet and can scroll through, you can access the above-mentioned platforms. So, if you are a student on the lookout for platforms that can help you best craft a great paper that would make your supervisors smile at you, then consider using any of the services listed above. They have been carefully curated just for you for this purpose. A few words in conclusion Your future is in your hands. Likewise, a sage affirms that a man is the architect of his destiny. This means that, as humans, we can pick from available options and carefully plan for the life we want to see. The same goes for you as a student today seeking to be one of the best in his class or level. The truth is, it is your choice to either ask for help or not. If you cannot write your essay, contacting professional essay writing services in the USA would be a great choice. Seeing that the essay writing services highlighted above are available to tend to all the writing needs of students, it becomes easier to pass courses. Most courses and subjects have a larger chunk of their marks allocated to assignments and papers/essays, which expert writers are ready to take; perhaps you cannot do it. Even if you can but still require an expert's perspective, you should buy your essay from these platforms. Take a step in the right direction toward your stellar academic future today! Contact Details Martina Brenwood usa_writers@best-essay-services.com

January 04, 2023 11:15 PM Eastern Standard Time

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