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Dr. Nirmal Joshi Named Chair of Patient Safety Authority Board

Patient Safety Authority

Governor Tom Wolf has appointed Nirmal Joshi, MD, FACP, as chair of the Patient Safety Authority (PSA) board of directors. Dr. Joshi succeeds Dr. Denise Johnson, Acting Secretary of Health and Physician General for Pennsylvania, who served as PSA’s board chair for the past year. An internal medicine physician, Dr. Joshi brings extensive experience in clinical quality, patient safety, research, and executive leadership to the role. He currently serves as the chief medical officer of Population Health for Mount Nittany Health System in State College. He is also president of the Joshi Health Foundation in Mechanicsburg—a nonprofit organization he founded to provide free healthcare to those who are unable to afford it. In 2016, Becker’s Hospital Review recognized him as one of “100 hospital and system CMOs to know.” He was also named one of “150 Living Legacy Contributors” to the Capital City by the Harrisburg SusqueCentennial Commission. Dr. Joshi has served on the Board of Asian Indian Americans of Central PA and the State Board of Medicine and has helped start new health systems in India where he began his medical education. Dr. Joshi received his Bachelor of Medicine-Bachelor of Surgery from King George Medical College and fellowship training in infectious diseases from the Milton S. Hershey Medical Center. “My special interests in clinical quality, patient safety, and improving physician-patient communication align with PSA’s work to bring awareness of issues and advance best practices in patient safety,” said Dr. Joshi. “I am honored and pleased to lead an organization that is driving these ideas and offering solutions in Pennsylvania and around the globe.” “Dr. Joshi’s passion for clinical quality and patient safety, his extensive experience in executive leadership, and his humanitarian approach are a welcome addition to the PSA,” said Regina Hoffman, executive director. “We are very much looking forward to having him at the helm.” Today, Pennsylvania leads the country in patient safety advocacy as the only U.S. state that requires healthcare facilities to report harmful events, as well as those that do not result in patient harm (i.e., near misses) but may be a harbinger of a potentially serious problem. The PSA analyzes those events, facilitates statewide performance improvement projects, and shares the information globally. The PSA is an independent state agency that collects and analyzes patient safety data to improve safety outcomes and help prevent patient harm. http://patientsafety.pa.gov/ About PSA Established under the Medical Care Availability and Reduction of Error (MCARE) Act of 2002, the PSA, an independent state agency, collects and analyzes patient safety data to improve safety outcomes and help prevent patient harm. http://patientsafety.pa.gov/ Contact Details Bev Volpe +1 609-230-4696 bev@madisongall.com Company Website http://patientsafety.pa.gov/

July 08, 2022 10:00 AM Eastern Daylight Time

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Sevita Named Among “America’s Best Employers for Diversity”

Sevita

Sevita, a leading national provider of home and community-based health care and support services, has been named by Forbes as one of “America’s Best Employers for Diversity.” The recognition was presented to organizations that have demonstrated diversity in staffing and leadership, as well as being proactive in diversity and inclusion initiatives. This marks the second consecutive year that Sevita has been named to the list. “As an organization that values integrity, respect, inclusion, and growth, earning this distinction as one of the country’s most diverse employers is wonderfully important to us,” said Natasha Hudspeth, Sevita’s Chief Diversity Officer and VP of Talent. “We are an organization that puts people at the center of all we do. We believe that everyone deserves a safe, welcoming space where they can grow and thrive. This commitment to respect and inclusion extends to everyone in our community, from the people we serve to those we employ. Investing in programs that enhance the experience for our employees is a priority for us. We serve incredibly diverse populations, and the diversity of our teams reflects that. Better representation yields better outcomes for our team members, the individuals in our care, their families, and our communities.” According to Forbes, the publication “partnered with market research company Statista to compile [this year’s list]. To determine the ranking, Statista surveyed 60,000 Americans working for businesses with at least 1,000 employees and pinpointed the companies they identified as most dedicated to diversity, equity and inclusion.” Recent diversity-focused initiatives undertaken at Sevita include: The launch of an Inclusion Council to enhance the employee experience and fuel Sevita’s commitment and common purpose to provide quality care to those we serve A company-wide tour of listening sessions and focus groups across the range of experiences and professional levels of the organization to learn what helps employees feel most valued Investment in educational opportunities that will leverage an online learning library which has been made accessible to all employees “We continue to prioritize diversity, equity, inclusion, and belonging at Sevita, and it is affirming that our team members are reporting that these actions have translated to their employee experience,” adds Hudspeth. Sevita was previously recognized by Forbes as one of “America’s Best Employers by State” (2019; then operating as The MENTOR Network). Additional information about the methodology Survey participants were asked to rate their organizations on criteria such as age, gender, ethnicity, disability and sexual orientation equality, as well as that of general diversity. Responses were reviewed for potential diversity gaps. Statista then asked respondents belonging to underrepresented groups to nominate organizations other than their own. The final list ranks the 500 employers that not only received the most recommendations, but also boast the most diverse boards and executive ranks and the most proactive diversity and inclusion initiatives. ### Sevita is a leading provider of community-based specialized health care, inspired by our core values of respect, integrity, inclusion and growth. We provide people with quality services and individualized supports that lead to growth and independence, regardless of the physical, intellectual, or behavioral challenges they face. We've made this our mission for more than 50 years. Today our team members continue to innovate and enhance care for the 50,000+ individuals we serve. Contact Details Melissa Patricio media@sevitahealth.com Company Website https://sevitahealth.com/

July 07, 2022 12:30 PM Eastern Daylight Time

First version of the SleepX APP has been uploaded to the Google Play Store

Appyea

SleepX, a subsidiary of AppYea (OTC: APYP) a Company that is focused on the development of accurate wearable monitoring solutions to treat sleep apnea and snoring, announces that the first version of the SleepX APP has been uploaded to the Google Play Store. Without a wristband, the current version can be used for breath monitoring, snoring detection and intensity, as well as the amount of snoring per sleep session. The app also provides the user a breathing graph as well as a recording each sleep session. The app is available for free download for all versions of Android starting with version 7.0. "We decided to upload the first version for free, to increase people awareness of the importance of quality of proper breathing during sleep," said Bary Molchadsky, founder of SleepX and chairman of AppYea. “Poor sleep is associated with a compromised immune system, heart problems, reduced physical and mental performance, mood problems, obesity and many other health problems”, said Neil Kline, Founder & former CEO of the American Sleep Association, and a AppYea Board Member. “Unfortunately, most people with sleep disorder breathing problems, like sleep apnea, are undiagnosed and untreated. Our goal with this unique technology is to raise awareness and improve sleep quality so individuals can live healthier and more fulfilling lives.” Free download the SleepX APP for Android AppYea continues in-depth tests and calibration of DreamIT, its wearable data-driven wristband to treat snoring. The wearable contains a vibration motor and sensors that measure real-time physiological indications such as movement, pulse, blood oxygen level, blood pressure, etc. and send the data to the SleepX app on the user smartphone. Unique algorithms combine all data in real time and decide when to activate the vibration, at what intensity, and its duration. The gentle vibration takes you out of deep sleep into a lighter phase, a transition that trains user to breathe properly. Over a short amount of time, user’s brain and body use biofeedback to teach itself to sleep in the correct position and proper breathing technique on its own, leading to improved night breathing over time. At the user's choice, it is possible to receive comprehensive statistical reports on sleep quality and sleep health, as well as alerts about critical health changes that require consultation and follow-up. In the coming months, the company plans to launch the SleepX APP on the APPLE STORE for iPhone users and start marketing DreamIT. SleepX is an Israeli research and development company recently acquired by AppYea. The Company has developed a unique product for monitoring and treating sleep apnea and snoring. The technology is protected by several international patents and the Company plans to start serial production in 2022. The Company currently focuses its activities on the development and commercialization of its flagship product DreamIT. Legal Notice Regarding Forward-Looking Statements This release includes forward-looking statements. Such statements involve risks and uncertainties which could cause actual results to differ materially from those set forth herein. No statement herein should be considered an offer or a solicitation of an offer for the purchase or sale of any securities. Although APYP believes that the expectations reflected in the forward-looking statements and the assumptions upon which they are based are reasonable, it can give no assurance that such expectations and assumptions will prove to have been correct. Forward-looking statements, which involve assumptions and describe our future plans, strategies, and expectations, are generally identifiable by use of the words "may," "will," "should," "could," "expect," "anticipate," "estimate," "believe," "intend," or "project" or the negative of these words or other variations on these words or comparable terminology. The reader is cautioned not to put undue reliance on these forward-looking statements, as these statements are subject to numerous factors and uncertainties, including but not limited to adverse economic conditions, intense competition, entry of new competitors and products, adverse federal, state and local government regulation, inadequate capital, unexpected costs and operating deficits, increases in general and administrative costs, unanticipated losses, financial condition and stock price, inability to carry out research, development and commercialization plans and other specific risks. APYP does not undertake any obligation to publicly update any forward-looking statement. Neither APYP nor SLEEPX are subject to the reporting requirements of the Securities and Exchange Commission under the Securities and Exchange Act of 1934 as amended. Contact Details AppYea inc. Bary Molchadsky +1 800-674-3561 info@appyea.com Company Website http://www.appyea.com

July 07, 2022 02:41 AM Eastern Daylight Time

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Sevita Chief Quality Officer Gerry Morrissey Inducted to Special Olympics Massachusetts Hall of Fame

Sevita

Sevita, a leading national provider of community-based health care and support services, is pleased to announce that our Chief Quality Officer, Gerry Morrissey, was inducted to the Special Olympics Massachusetts Hall of Fame on June 22, 2022, at the JFK Library in Boston. Morrissey is the 2022 recipient of the John “Jack” Brett Champions Award, which is given annually to someone who has supported and improved the lives of individuals with intellectual disabilities. A lifelong advocate for individuals with disabilities, Morrissey is a state and national human services leader and quality expert who devoted more than 30 years of his career to the Commonwealth of Massachusetts, including four years as assistant secretary for Disabilities and Community Services and more than a decade as commissioner of the Department of Developmental Services. He has led quality improvement for Sevita since 2007 across 41 states serving 55,000 individuals. "Special Olympics Massachusetts is so proud to honor Gerry Morrissey with the John "Jack" Brett Champions Award,” said Mary Beth McMahon, president and CEO. “Gerry has lived a life in the service of others, especially our neighbors with intellectual disabilities. Throughout his career from his time serving as the commissioner of the Department of Developmental Services, and now with Sevita, Gerry has put the needs and rights of people with disabilities at the forefront. He has always been a champion for us as such, we are excited to honor him with the Champions Award." Morrissey is the sixth recipient of the Champions Award. Past recipients include former State Representative Jim Brett; U.S. Labor Secretary Marty Walsh; Governor Charlie Baker; former Congressman Joe Kennedy; and State Senator Nick Collins. Morrissey is past president and board member of the National Association of State Directors of Developmental Disabilities (NASDDDS) and the recipient of the Ben Censoni Excellence in Public Service Award. He is a longtime supporter of Special Olympics Massachusetts and served on the Board of Directors from 2000 – 2009. Morrissey currently serves on the Board of Directors for the Boys & Girls Clubs of Dorchester, which awarded him the National Service to Youth Award, and remains an active supporter of and advocate for Best Buddies. “We are incredibly proud of Gerry for this incredible honor,” said Brett Cohen, chief operating officer for Sevita. “As a leader at the state and national level, Gerry’s influence and impact extends far beyond our organization and deep into the community, where his commitment to helping people live full and joyful lives of their own choosing, despite the challenges they face, is an example to us all.” ### Sevita is a leading provider of community-based specialized health care, inspired by our core values of respect, integrity, inclusion and growth. We provide people with quality services and individualized supports that lead to growth and independence, regardless of the physical, intellectual, or behavioral challenges they face. We've made this our mission for more than 50 years. Today our team members continue to innovate and enhance care for the 50,000+ individuals we serve. Contact Details Melissa Patricio media@sevitahealth.com Company Website https://sevitahealth.com/

July 06, 2022 11:00 AM Eastern Daylight Time

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New Jersey Partners with Shatterproof® and Horizon Blue Cross Blue Shield of NJ to Launch Online Substance Use Disorder Treatment Reference Guide

Shatterproof

New Jersey Human Services Commissioner Sarah Adelman announced today that New Jersey has launched a free, confidential, first-of-its-kind on-line tool to connect New Jerseyans in need with appropriate addiction treatment care and deliver user-friendly information about the quality of available programs. ATLAS, or Addiction Treatment Locator, Assessment, and Standards Platform, at www.TreatmentATLAS.org, offers an easy-to-use dashboard to allow individuals with substance use disorder and their loved ones to search for and compare participating programs using criteria such as location, services offered, and insurance accepted so they can find the best treatment for their unique needs. ATLAS was created by Shatterproof, a national nonprofit organization dedicated to reversing the addiction crisis in America. ATLAS has been made possible in New Jersey through a partnership with Humane Services and funding from Horizon Blue Cross Blue Shield of New Jersey. ATLAS evaluates addiction treatment programs’ use of evidence-based best practices and makes this information available to the public on its platform. Best practices are based on the Shatterproof National Principles of Care, which are evidence-based standards derived from the Surgeon General’s Report on Addiction, using data gathered through a combination of validated sources. “It’s vital to empower individuals and families confronting substance use disorder and help them make informed decisions,” Commissioner Adelman said. “This is yet another tool in our collective work to make addiction treatment as accessible as possible so individuals and families can get the help they need – because treatment works and recovery is attainable. Our goal, always, is to save lives. This is another way to do so.” ATLAS includes an assessment to help individuals understand the appropriate level of care they need. The platform also gathers and displays anonymous feedback from patients on their experiences at facilities. This feedback helps to inform others’ care decisions. Anyone who has received treatment from a facility in New Jersey can visit www.TreatmentATLAS.org to search for the facility and leave a patient review. ATLAS lists New Jersey addiction treatment facilities for various types of substance use disorder, including alcohol and opioid use disorder. “During a time when our nation’s addiction crisis is tragically at an all-time high and access to quality treatment is often hard to find, ATLAS is a critical new resource. When my son Brian needed addiction treatment, my family agonized trying to find him the right care. It was impossible to know who to trust,” Shatterproof Founder and CEO Gary Mendell said. “ATLAS is a sea change in the addiction world. It will give those in need and their families the transparent and trustworthy information my family never had and will help put more people on the path to recovery.” “Horizon is thrilled to be able to provide the funding needed to bring Shatterproof’s ATLAS to New Jersey,” said Suzanne Kunis, Vice President of Behavioral Health for Horizon BCBSNJ. “No one in crisis, dealing with substance use disorders, or worse, an overdose, should have to hope they guess right to find good care. The ATLAS Quality Measurement System gives New Jerseyans looking for treatment options the same kind of evidence-based quality and outcomes information they are used to getting about primary care doctors, specialists, and acute care hospitals. This is long overdue. We appreciate the providers who have joined us so far in sending a clear message that we are united here in New Jersey in our commitment to evidence-based treatment and to giving people meaningful information that helps them choose the right program and treatment partner.” ATLAS builds on existing efforts by New Jersey to connect individuals and families to treatment through the 1-844-ReachNJ helpline. ReachNJ is a 24-hour-a-day, 7 day-a-week addiction hotline where people who have substance use disorders (SUD) or friends and family of people with SUD can get immediate assistance and support from live, New Jersey-based, trained addiction counselors. An individual who calls the toll-free number will reach a live staff member who will help connect them to treatment, regardless of insurance status. ATLAS is fully available in English and Spanish and has several unique features including: • Feedback from other patients once a minimum threshold of 20 responses for the facility is met, updated every 24 hours; • An expert-approved Addiction Treatment Needs Assessment, created in collaboration with the American Society of Addiction Medicine (ASAM) and OpenBeds, to help guide the treatment search based on the individual’s needs and severity; • The ability to search and filter using criteria such as location, services offered and insurance accepted, as well as the opportunity to compare facilities. About Shatterproof: Shatterproof is a national nonprofit organization dedicated to reversing the addiction crisis in the United States. Shatterproof harnesses the models of business, the rigor of science and the power of a national movement to create change and save lives through three pillars of work: revolutionizing the addiction treatment system, breaking down addiction-related stigmas and supporting and empowering our communities. To learn more visit www.Shatterproof.org. Contact Details Shatterproof Lauren Lawson-Zilai +1 646-334-1024 press@shatterproof.org NJ Department of Human Services Tom Hester +1 609-292-3717 tom.hester@dhs.nj.gov Company Website https://www.shatterproof.org/

July 06, 2022 10:45 AM Eastern Daylight Time

US Digestive Health Launches the Largest Installation of Artificial Intelligence (AI) Systems for Colorectal Cancer Screening in the United States

US Digestive Health

US Digestive Health (“USDH”), a network of top-rated gastrointestinal (GI) practices, today announced that it is now offering patients AI-assisted colonoscopy screenings with the country’s largest installation of GI Genius™ intelligent endoscopy modules. In the U.S., colorectal cancer is the third most common form of diagnosed cancer and the second deadliest, with almost 150,000 new cases every year [1]. However, it’s also one of the most treatable cancers, with a 90% survival rate when it is detected and treated early. Colonoscopy has long been considered the gold standard for detecting polyps that can eventually lead to colorectal cancer. Now, patients at USDH have the strength of an AI-assisted option for screening with GI Genius TM — the first and only FDA-cleared, commercially available device that employs AI to help physicians detect polyps. US Digestive Health’s installation of GI Genius TM is the largest in the world and the first in Pennsylvania. The launch will give patients throughout southeastern, southwestern and central Pennsylvania wide-ranging access to the innovative technology and its enhanced capability. “GI Genius TM is a major breakthrough in colorectal cancer screening. In real time, it can help physicians identify hard-to-detect and potentially cancerous polyps,” said Dr. Dale Whitebloom, US Digestive Health’s Chief Medical Officer. “We begin our screening colonoscopies at age 45, which is the most up-to-date recommendation by the U.S. Preventive Services Task Force and American Cancer Society. Adding GI Genius TM gives us yet another tool to help protect our patients from the scourge of cancer.” The GI Genius TM module uses advanced AI software to highlight suspicious areas with a visual marker in real time — serving as the gastroenterologist’s vigilant second observer with a sensitivity rate per lesion of 100% [2]. A study published on March 15 in Gastroenterology, the official medical journal of the American Gastroenterological Society, found that the use of GI Genius TM in conjunction with a colonoscopy can decrease polyp miss rates by nearly 50%, while other studies have shown that AI-assisted colonoscopy can increase detection rates by up to 14% [3],[4]. Jerry Tillinger, CEO of US Digestive Health, said, “Our mission is to prevent colorectal cancer, and AI-assisted colonoscopy is an incredible advancement in protecting the people of Pennsylvania from this terrible disease. We’re proud to collaborate with Medtronic, as well as our endoscopy partners, AMSURG and PE GI Solutions, to roll out the largest installation of GI Genius TM not only in the United States but also in the world. As a result, US Digestive Health patients now have access to GI Genius TM -assisted colonoscopies.” US Digestive Health was formed in 2019 by Amulet Capital Partners, LP (“Amulet”), a middle-market private equity investment firm based in Greenwich, CT, focused exclusively on the healthcare sector, in partnership with member practice partner physicians. For more information or to schedule a GI Genius TM -enabled colonoscopy, please visit https://usdigestivehealth.com/. ______________________________________________________________________________________ [1] Cancer.Net. Colorectal Cancer: Statistics. January 2020. Available at: https://www.cancer.net/cancer-types/colorectal-cancer/statistics. Accessed January 22, 2021. [2] Sensitivity calculated as true positive frame rate. GI Genius™ intelligent endoscopy module [instructions for use]. Mansfield, MA: Medtronic; 2021. [3] Hassan C, et al. New artificial intelligence system: first validation study versus experienced endoscopists for colorectal polyp detection. Gut. 2020;69(5):799-800 [4] Repici A, Badalamenti M, Maselli R, et al. Efficacy of real-time computer-aided detection of colorectal neoplasia in a randomized trial. Gastroenterology. 2020; 159:512–520.e7. About US Digestive Health US Digestive Health oversees a network of over 150 gastroenterology providers and has 26 locations, 15affiliated ambulatory surgery centers, and more than 800 total employees in Pennsylvania. They are at the forefront of the rapidly advancing science of digestive health, bringing new insight into the care, treatment, and prevention of digestive health disorders. The practices that have joined the US Digestive Health network are: Digestive Disease Associates of Berks and Chester Counties; Main Line Gastroenterology Associates of Chester, Delaware, and Montgomery Counties; Regional Gastroenterology of Lancaster County; Carlisle Digestive Disease Associates of Cumberland County; West Chester Gastrointestinal Group of Chester County; Hillmont G.I. of Montgomery County; The Center for GI Health of Bucks and Montgomery Counties; and Gastrointestinal Specialists of Philadelphia, Montgomery, and Bucks Counties. About Amulet Capital Partners, LP Amulet Capital Partners, LP is a middle-market private equity investment firm based in Greenwich, CT, focused exclusively on the healthcare sector. Amulet seeks to achieve long-term capital appreciation through privately negotiated investments in companies. Amulet Capital Partners focuses on those segments it believes have the most attractive long-term fundamentals with a target investment size generally between $25 million to $150 million. For additional information, please visit www.amuletcapital.com. INDICATIONS GI Genius™ intelligent endoscopy module is a computer-assisted reading tool designed to aid endoscopists in detecting colonic mucosal lesions (such as polyps and adenomas) in real time during standard white light endoscopy examinations of patients undergoing screening and surveillance endoscopic mucosal evaluations. The GI Genius™ computer-assisted detection device is limited for use with standard white-light endoscopy imaging only. This device is not intended to replace clinical decision-making. ### Contact Details LevLane Lauren Stralo +1 484-747-9692 lstralo@levlane.com Company Website https://usdigestivehealth.com

July 06, 2022 08:03 AM Eastern Daylight Time

Kidney Transplants Continue to Rise Nationally

United Network for Organ Sharing

A new report shows continued increases in the number of lifesaving kidney transplants taking place across the country, according to data compiled by United Network for Organ Sharing (UNOS). UNOS is the engine that powers the national donation and transplant system, serving as the Organ Procurement and Transplantation Network (OPTN) under federal contract. Following changes in March of 2021 to how deceased donor kidneys were allocated, an early data report showed increases in the number of transplants and expanded equity, especially amongst historically marginalized groups. Now, with one full year of post-implementation data available, the new report shows a 16% increase in kidney transplants across the nation, including for the following groups: 23% for Black patients 29% for Hispanic patients 20% for Asian patients 36% for people with longer times on dialysis 63% for pediatric patients 79% for highly-sensitized patients, or those with more difficulty finding a compatible donor organ This data remains consistent with previous reports that showed similar, positive results for the same patient groups. “We continue to see positive results for patients and families following changes we enacted in 2021,” said UNOS CEO Brian Shepard. “Getting to this point means bringing together a diverse group of physicians, patients, advocates, donor families and others to develop policies that continue to improve the national system and save more lives. But even as we see transplants rise and equity improving, there is more work to do and we are committed to building on these and other successes.” The report also showed an increase in the number of kidneys that were not utilized. In keeping with the National Academies of Sciences, Engineering and Math (NASEM) recommendations, UNOS and stakeholders across the nation are committed to working together to find new ways to incentivize the use of more kidneys. Ongoing efforts to achieve this goal include the UNOS-developed offer-filters tool for transplant programs, expanding the use of predictive analytics in decision making, and more. Additionally, the OPTN Kidney Transplantation Committee will continue to monitor the impact and results of this policy. About UNOS United Network for Organ Sharing (UNOS) is a non-profit, charitable organization that serves as the Organ Procurement and Transplantation Network (OPTN) under contract with the federal government. The OPTN helps create and define organ allocation and distribution policies that make the best use of donated organs. This process involves continuously evaluating new advances and discoveries so policies can be adapted to best serve patients waiting for transplants. All transplant programs and organ procurement organizations throughout the country are OPTN members and are obligated to follow the policies the OPTN creates for allocating organs. Contact Details United Network for Organ Sharing Anne Paschke +1 804-782-4730 newsroom@unos.org Company Website https://unos.org

July 05, 2022 01:25 PM Eastern Daylight Time

Vascudyne Receives BioBusiness Award from Regenerative Medicine Minnesota for Treatment of Nerve Injury

Vascudyne, Inc.

Vascudyne, Inc., a biotechnology trailblazer in regenerative medicine, announced today that it was awarded a grant from Regenerative Medicine Minnesota for a project titled “Development of a Peripheral Nerve Wrap Using Regenerative Engineering Tissue Tube”. The one-year, $100,000 grant will commence in June 2022 and utilize Vascudyne’s TRUE™ Tissue technology that is unique and 100% natural. The TRUE Tissue allogeneic biomaterial is completely biological, non-immunogenic and regenerates by the host. Nothing synthetic or artificial is ever used in the manufacturing process, in contrast to other regenerative medicine soft tissue biomaterials made from synthetic polymer-based scaffolds that slowly degrade in the body and may lead to adverse immune response. Chronic nerve compression is one of the most common peripheral nerve injuries with carpal tunnel syndrome being the most common type of nerve compression affecting 3-6% of the general population. Tissues isolated from the patient are used in surgery but have shortcomings such as donor site morbidity, limited availability, and risk of surgical complications. “We are excited to expand our TRUE Tissue platform technology to other soft tissue applications such as nerve repair,” said Rick Murphy, Vascudyne’s Chief Operating Officer. “The exquisite regenerative properties of our 100% biological biomaterial combined with its non-immunogenic properties and off-the-shelf availability are a perfect fit for addressing the challenging nerve injury applications. Demonstrating these benefits in a preclinical nerve injury model will greatly advance the field of peripheral nerve injury and offer a promising alternative to current treatments that often lack complete and functional nerve repair.” Vascudyne has prioritized commercialization of its cardiovascular products and recently announced the first clinical results of its regenerative vascular conduit for hemodialysis access. “While we are initially focusing on cardiovascular applications for our TRUE Tissue technology, we continue research and development efforts in other soft tissue applications such as nerve injury repair,” stated Dr. Zeeshan Syedain, Vascudyne’s Chief Scientific Officer. “This grant from the Regenerative Medicine Minnesota will help accelerate our preclinical animal study timeline and demonstrate safety and efficacy of the TRUE Tissue technology as a peripheral nerve wrap.” Vascudyne licensed its proprietary TRUE Tissue technology developed by world renowned tissue engineering leader Robert Tranquillo, PhD, Distinguished McKnight University Professor, and his colleagues from the University of Minnesota in 2017. TRUE Tissue products are not available for commercial sale. About Vascudyne Headquartered in the heart of Medical Alley in Minnesota, Vascudyne is on a mission to improve patient care with regenerative biomaterials that are inspired by nature. Vascudyne, a privately held company founded in 2014, uses the TRUE™ Tissue technology to develop TRUE to Nature™ biomaterials for soft tissue repair and replacement. For more information, please visit https://www.vascudyne.com/. About TRUE™ Tissue Technology TRUE™ Tissue is developed from cells isolated from donor tissue and is 100% biological. There are no synthetic materials or chemical fixation used, and implanted tissues are completely cell-derived and acellular. The TRUE™ Tissue technology can be readily shaped into tubes, sheets, and other geometries making it suitable for many soft tissue applications, is mechanically comparable to native tissues, and is a ready to use, off-the-shelf allograft. Forward Looking Statements This announcement contains forward-looking statements. Such statements may include, without limitation, statements identified by words such as "projects," "may," "will," "could," "would," "should," "believes," "expects," "anticipates," "estimates," "intends," "plans," "potential" or similar expressions. These statements relate to future events or Vascudyne’s clinical development programs, reflect management’s current beliefs and expectations and involve known and unknown risks, uncertainties and other factors that may cause Vascudyne’s actual results, performance or achievements to be materially different. Vascudyne undertakes no obligation to publicly update any forward-looking statements, whether as a result of new information, future presentations or otherwise, except as required by applicable law. Contact Details Vascudyne, Inc. Sandy Williams, Marketing Director +1 952-412-5975 swilliams@vascudyne.com Company Website https://vascudyne.com/

June 30, 2022 09:23 AM Eastern Daylight Time

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What Your Nails Say About Your Health

YourUpdateTV

A video accompanying this announcement is available at: https://youtu.be/LI5F93klWMQ Did you know your nails can reveal clues to your overall health? Take a close look at your fingernails. Are they strong and healthy looking? Or do you see ridges, dents, or areas of unusual color or shape? Many in your audience might be asking, am I taking good care of my nails? Here's what you need to know to keep your nails in tiptop shape from Dr. Dana Stern, board-certified dermatologist and Assistant Clinical Professor of Dermatology at the Mount Sinai Medical Center in New York City. Dr. Stern is the only dermatologist who devotes her entire practice to nail diagnosis, treatment, and surgery and she’s a go-to dermatologist for patients seeking advice on how to treat nail conditions and gel damage, as well as how to keep their nails healthy and beautiful. Recently relaunched by Rare Beauty Brands and hailed by celebrities as a nail miracle, Dr. Dana’s famous Nail Renewal System is an easy-to-use botanically formulated product that utilizes plant-based science to exfoliate and hydrate nails to combat brittle, ridged, weak and over-processed nails within minutes of the first application. FOR MORE INFORMATION VISIT: DRDANANAILS.COM Contact Details YourUpdateTV +1 212-736-2727 yourupdatetv@gmail.com

June 29, 2022 11:00 AM Eastern Daylight Time

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